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Human Physiology, 7/e
Stuart I Fox, Pierce College

Enzymes and Energy

True or False Quiz

Please answer all questions



1

Enzymes cannot work outside the cells that synthesize them. (p. 84)
A)True
B)False
2

Enzymes are not used up by the reactions they catalyze. (p. 84)
A)True
B)False
3

The amount of energy released by a chemical reaction is much greater when it is catalyzed by an enzyme. (p. 85)
A)True
B)False
4

An enzyme works by increasing the activation energy of a chemical reaction. (p. 85)
A)True
B)False
5

The chemical reactions of living cells could not occur in the absence of enzymes. (p. 84)
A)True
B)False
6

A substrate molecule binds to certain amino acids that line the active site of an enzyme. (p. 85)
A)True
B)False
7

Hydrolases are enzymes that remove water from organic molecules (that is, remove -H and -OH chemical groups and produce water as a reaction product, known as dehydration). (p. 86)
A)True
B)False
8

All enzyme names end with the suffix -ase. (p. 86)
A)True
B)False
9

Enzymes do not increase the energy content of the reactants (or substrates). (p. 85)
A)True
B)False
10

One reason enzymes are so effective is that each enzyme can catalyze a broad range of metabolic reactions. (p. 84)
A)True
B)False
11

Isoenzymes are enzymes with identical structures, but which perform different roles in different cells. (p. 86)
A)True
B)False
12

The active sites of isoenzymes are not affected by the structural differences that distinguish one isoenzyme from another. (p. 86)
A)True
B)False
13

Skeletal and cardiac muscle have different forms of creatine phosphokinase. (p. 86)
A)True
B)False
14

The rate of an enzymatic reaction depends on the concentration of enzyme present, but not on the concentration of the substrate. (p. 88)
A)True
B)False
15

The higher the temperature, the faster the rate of an enzymatic reaction will be. (p. 87)
A)True
B)False
16

Human enzymes all have approximately the same temperature optimum, but highly varied pH optima. (p. 87)
A)True
B)False
17

Although these enzymes selectively remove phosphate groups, the phosphatase from the prostate functions best at a lower pH than the phosphatase from bone tissue. (p. 88)
A)True
B)False
18

Many enzymes cannot function when they are completely purified and isolated from their natural chemical surroundings. (p.88)
A)True
B)False
19

Metal ions that aid the function of enzymes can be called either coenzymes or cofactors for those enzymes. (p. 88)
A)True
B)False
20

Cofactors are metal ions that sometimes bind to the active site of an enzyme along with its substrate in order for the enzyme to function at its optimal rate.(p. 88)
A)True
B)False
21

Carbonic anhydrase is an enzyme that can catalyze the breakdown of carbonic acid (H2CO3) into carbon dioxide (CO2) and water (H2O), but it cannot catalyze the reverse reaction. (p. 89)
A)True
B)False
22

The reversal of some enzyme-catalyzed reactions may require a different set of enzymes than the ones that make the reaction go in a forward direction. (p. 89)
A)True
B)False
23

If there is a reversible chemical reaction between two molecules A and B, and more B than A is present at a given moment, then the law of mass action predicts this reaction will go toward the left (that is, more B will be converted to A). (p. 89)
A)True
B)False
24

The nine-step enzymatic conversion of glucose to pyruvic acid is a metabolic pathway. The one-step enzymatic conversion of CO2 and H2O to carbonic acid is not. (p. 89)
A)True
B)False
25

An intermediate in a metabolic pathway may serve as the substrate for two or more different enzymes that catalyze reactions leading in different directions. (p. 89)
A)True
B)False
26

Some metabolic end-products can deactivate or inhibit the very enzymes that are responsible for their production. (p. 89)
A)True
B)False
27

Allosteric inhibitors bind directly to the active site of an enzyme to keep it from interacting with its normal substrate. (p. 89)
A)True
B)False
28

Suppose enzyme3 catalyzes the third step in a metabolic pathway where intermediate G is converted to intermediate H. An inborn error of metabolism resulting in a defective enzyme3 would result in a surplus of G and deficiency of H. (p. 90)
A)True
B)False
29

Albinism is the result of an inherited defect in an enzyme that produces skin pigment. (p. 91)
A)True
B)False
30

The fundamental point of cellular metabolism is to increase the amount of entropy in the system. (p. 93)
A)True
B)False
31

Entropy is a measure of the amount of free energy in a system. (p. 92)
A)True
B)False
32

Photosynthesis is an endergonic reaction.(p. 92)
A)True
B)False
33

The human body is unable to carry out any endergonic reactions because it does not have any photosynthetic pigments and cannot synthesize organic nutrients. (p. 93)
A)True
B)False
34

When glucose is burned in a dish, it breaks down to CO2 + H2O. This demonstrates that the glucose contains more energy than the CO2 + H2O it was made from. (p. 92)
A)True
B)False
35

The complete oxidation of glucose to CO2 + H2O is an exergonic reaction. (p. 92)
A)True
B)False
36

The oxidation of 1 gram of glucose to CO2 + H2O will release more calories when done in small, enzymatically-controlled steps within a cell than when done in a single step by simply touching a match to a pile of glucose. (p. 92)
A)True
B)False
37

One Calorie will raise the temperature of one liter of water one degree Celsius. (p. 93)
A)True
B)False
38

A cell must maintain a state of low entropy to stay alive. (p. 93)
A)True
B)False
39

All exergonic reactions in a cell are directly linked to endergonic reactions. (p. 93)
A)True
B)False
40

The endergonic reaction to which most exergonic reactions of a cell are linked is ATP ? ADP + Pi + Energy. (p. 93)
A)True
B)False
41

Reduction means a process in which an atom or molecule gains electrons. (p. 93)
A)True
B)False
42

Oxidation means a reaction in which some atom or molecule combines with oxygen. (p. 94)
A)True
B)False
43

In the course of performing its role, an oxidizing agent becomes oxidized. (p. 94)
A)True
B)False
44

It is impossible for an oxidation reaction to occur without a reduction reaction occurring simultaneously along with it. (p. 94)
A)True
B)False
45

If a molecule picks up two hydrogen atoms, it becomes reduced. (p. 94)
A)True
B)False
46

It is possible for the same molecule to serve as both an oxidizing agent and a reducing agent, alternating from one to the other. (p. 94)
A)True
B)False
47

The structure of the coenzyme NAD is very similar to the structure of the universal energy carrier ATP. (p. 95)
A)True
B)False
48

NADH is a reducing agent. (p. 95)
A)True
B)False
49

NAD is derived from niacin, a water soluble vitamin known as B3. (p. 95)
A)TRUE
B)FALSE
50

FAD can accept two electrons and become FADH2, but NAD can only accept one electron and become NADH. (p. 95)
A)TRUE
B)FALSE
51

Since the vitamin riboflavin (vitamin B2) is converted to a coenzyme that transfers electrons in the energy- producing reactions of the body, you can get extra energy by eating riboflavin supplements. (p. 95)
A)TRUE
B)FALSE
52

In a hypothetical reaction XH2 + Y X + YH2, the compound Y is an oxidizing agent. (p. 94)
A)TRUE
B)FALSE
53

In a hypothetical reaction XH2 + Y X + YH2, the ompound Y becomes oxidized. (p. 94)
A)TRUE
B)FALSE