A comma splice is an error similar to a fused sentence. A fused sentence joins two independent (main) clauses without a conjunction and/or proper punctuation. A comma splice joins two complete sentences with a comma. However, a comma is not strong enough to join two independent (main) clauses. You can correct a comma splice by using the same five methods used to correct fused sentences.
NOT:
Mecca is Islam’s holiest city, Medina is also an important religious center.
BUT:
Mecca is Islam’s holiest city. Medina is also an important religious center.
OR:
Mecca is Islam’s holiest city, but Medina is also an important religious center.
OR:
Mecca is Islam’s holiest city; Medina is also an important religious center.
OR:
Mecca is Islam’s holiest city; however, Medina is also an important religious center.
OR:
Although Mecca is Islam’s holiest city, Medina is also an important religious center.