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Clinical Case 18
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1

Which of the following statements is correct with regard to bone mineral metabolism in children with juvenile rheumatoid arthritis (JRA)?
A)It is often abnormal in children with JRA with a history of active synovitis.
B)Bone mineral metabolism is altered predominantly affecting age-related development of trabecular bone.
C)Regional epiphyseal closure may be delayed.
D)Changes in bone mineral metabolism are thought to be the result of decreased levels of cytokines.
E)Steroid treatment is primarily the cause of the abnormalities seen in bone mineral metabolism in children with JRA.





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