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Pharmacotherapy 7th Edition
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Pharmacotherapy: A Pathophysiologic Approach, 7/e

Joseph T. DiPiro
Robert L. Talbert
Gary C. Yee
Gary R. Matzke
Barbara G. Wells
L. Michael Posey

ISBN: 007147899x
Copyright year: 2008

Table of Contents



SECTION 1
Foundation Issues
Section Editor: L. Michael Posey

1. Pharmacoeconomics: Principles, Methods, and Applications
Lisa A. Sanchez

2. Health Outcomes and Quality of Life
Stephen Joel Coons

3. Evidence-Based Medicine
Elaine Chiquette and L. Michael Posey

4. Documentation of Pharmacy Services
George E. MacKinnon, III and Neil J. MacKinnon

5. Clinical Pharmacokinetics and Pharmacodynamics
Larry A. Bauer

6. Pharmacogenetics
Larisa H. Cavallari and Y. W. Francis Lam

7. Pediatrics
Milap C. Nahata and Carol Taketomo

8. Geriatrics
Catherine I. Starner, Shelly L. Gray, David R. P. Guay, Emily R. Hajjar, Steven M. Handler, and Joseph T. Hanlon

9. Pharmacoepidemiology
Andy Stergachis, Thomas K. Hazlet, and Denise Boudreau

10. Clinical Toxicology
Peter A. Chyka

11. Emergency Preparedness: Identification and Management of Biological Exposures
Colleen M. Terriff, Jason E. Brouillard, Lisa T. Costanigro, and Jessica S. Gruber

12. Emergency Preparedness: Identification and Management of Chemical and Radiological Exposures
Greene Shepherd and Richard B. Schwartz

SECTION 2
Cardiovascular Disorders
Section Editor: Robert L. Talbert

13. Cardiovascular Testing.
Robert Chilton and Robert L. Talbert

14. Cardiopulmonary Resuscitation
Jeffrey F. Barletta and Jeffrey L. Wilt

15. Hypertension
Joseph J. Saseen and Eric J. MacLaughlin

16. Heart Failure
Robert B. Parker, Jo E. Rodgers, and Larisa H. Cavallari

17. Ischemic Heart Disease
Robert L. Talbert

18. Acute Coronary Syndromes
Sarah A. Spinler and Simon de Denus

19. The Arrhythmias
Cynthia A. Sanoski, Marieke Dekker Schoen, and Jerry L. Bauman

20. Diastolic Heart Failure and the Cardiomyopathies
Jean M. Nappi and Robert L. Page, II

21. Venous Thromboembolism
Stuart T. Haines, Daniel M. Witt, and Edith A. Nutescu

22. Stroke
Susan C. Fagan and David C. Hess

23. Hyperlipidemia
Robert L. Talbert

24. Peripheral Arterial Disease
Barbara J. Hoeben and Robert L. Talbert

25. Use of Vasopressors and Inotropes in the Pharmacotherapy of Shock
Robert MacLaren, Maria I. Rudis, and Joseph F. Dasta

26. Hypovolemic Shock
Brian L. Erstad

SECTION 3
Respiratory Disorders
Section Editor: Robert L. Talbert

27. Introduction to Pulmonary Function Testing
Jay I. Peters and Stephanie M. Levine

28. Asthma
H. William Kelly and Christine A. Sorkness

29. Chronic Obstructive Pulmonary Disease
Dennis M. Williams and Sharya V. Bourdet

30. Pulmonary Hypertension
Robert L. Talbert, Rebecca Boudreaux, and Rebecca L. Owens

31. Drug-Induced Pulmonary Diseases
Hengameh H. Raissy, Michelle Harkins, and Patricia L. Marshik

32. Cystic Fibrosis
Gary Milavetz

SECTION 4
Gastrointestinal Disorders
Section Editor: Joseph T. DiPiro

33. Evaluation of the Gastrointestinal Tract
Keith M. Olsen, Marie A. Chisholm, and Mark W. Jackson

34. Gastroesophageal Reflux Disease
Dianne B. Williams and Robert R. Schade

35. Peptic Ulcer Disease
Rosemary R. Berardi and Lynda S. Welage

36. Inflammatory Bowel Disease
Brian A. Hemstreet and Joseph T. DiPiro

37. Nausea and Vomiting
Cecily V. DiPiro

38. Diarrhea, Constipation, and Irritable Bowel Syndrome
William J. Spruill and William E. Wade

39. Portal Hypertension and Cirrhosis
Julie M. Sease, Edward G. Timm, and James J. Stragand

40. Drug-Induced Liver Disease
William R. Kirchain and Rondall E. Allen

41. Pancreatitis
Rosemary R. Berardi and Patricia A. Montgomery

42. Viral Hepatitis
Paulina Deming, Renee-Claude Mercier, and Manjunath P. Pai

43. Drug Therapy Individualization in Patients with Hepatic Disease or Genetic Alterations in Drug Metabolizing Activity
Y. W. Francis Lam

SECTION 5
Renal Disorders
Section Editor: Gary R. Matzke

44. Quantification of Renal Function
Thomas C. Dowling

45. Acute Renal Failure
William Dager and Anne P. Spencer

46. Chronic Kidney Disease: Progression-Modifying Therapies
Melanie S. Joy, Abhijit Kshirsagar, and Nora Franceschini

47. Chronic Kidney Disease: Management of Complications
Joanna Q. Hudson

48. Hemodialysis and Peritoneal Dialysis
Edward F. Foote and Harold J. Manley

49. Drug-Induced Kidney Disease
Thomas D. Nolin and Jonathan Himmelfarb

50. Glomerulonephritis
Alan H. Lau

51. Drug Therapy Individualization for Patients with Renal Insufficiency
Gary R. Matzke and Reginald F. Frye

52. Disorders of Sodium and Water Homeostasis
James D. Coyle, Melanie S. Joy, and Gerald A. Hladik

53. Disorders of Calcium and Phosphorus Homeostasis
Amy Barton Pai, Mark Rohrscheib, Melanie S. Joy, and Gerald A. Hladik

54. Disorders of Potassium and Magnesium Homeostasis
Donald F. Brophy and Todd W. B. Gehr

55. Acid–Base Disorders
John W. Devlin, Gary R. Matzke, and Paul M. Palevsky

SECTION 6
Neurologic Disorders
Section Editor: Barbara G. Wells

56. Evaluation of Neurologic Illness
Susan C. Fagan and Fenwick T. Nichols

57. Multiple Sclerosis
Jacquelyn L. Bainbridge and John R. Corboy

58. Epilepsy
Susan J. Rogers and Jose E. Cavazos

59. Status Epilepticus
Stephanie J. Phelps, Collin A. Hovinga, and James W. Wheless

60. Acute Management of the Brain Injury Patient
Bradley A. Boucher and Shelly D. Timmons

61. Parkinson’s Disease
Jack J. Chen, Merlin V. Nelson, and David M. Swope

62. Pain Management
Terry J. Baumann and Jennifer Strickland

63. Headache Disorders
Deborah S. Minor and Marion R. Wofford

Psychiatric Disorders
Section Editor: Barbara G. Wells

64. Evaluation of Psychiatric Illness
Patricia A. Marken, Mark E. Schneiderhan, and Stuart Munro

65. Childhood Disorders
Julie Ann Dopheide, Jane Tran Tesoro, and Michael Malkin

66. Eating Disorders
Steven C. Stoner

67. Alzheimer’s Disease
Patricia W. Slattum, Russell H. Swerdlow, and Angela Massey Hill

68. Substance-Related Disorders: Overview and Depressants, Stimulants, and Hallucinogens
Paul L. Doering and Lisa A. Boothby

69. Substance-Related Disorders: Alcohol, Nicotine, and Caffeine
Paul L. Doering, W. Klugh Kennedy, and Lisa A. Boothby

70. Schizophrenia
M. Lynn Crismon, Tami R. Argo, and Peter F. Buckley

71. Depressive Disorders
Christian J. Teter, Judith C. Kando, Barbara G. Wells, and Peggy E. Hayes

72. Bipolar Disorder
Shannon J. Drayton and Benjamin L. Weinstein

73. Anxiety Disorders I: Generalized Anxiety, Panic, and Social Anxiety Disorders
Cynthia K. Kirkwood and Sarah T. Melton

74. Anxiety Disorders II: Posttraumatic Stress Disorder and Obsessive-Compulsive Disorder
Cynthia K. Kirkwood, Eugene H. Makela, and Barbara G. Wells

75. Sleep Disorders
John M. Dopp and Bradley G. Phillips

76. Developmental Disabilities
Nancy Brahm, Jerry McKee, and Robert C. Brown

SECTION 8
Endocrinologic Disorders
Section Editor: Robert L. Talbert

77. Diabetes Mellitus
Curtis L. Triplitt, Charles A. Reasner, II, and William L. Isley

78. Thyroid Disorders
Steven I. Sherman and Robert L. Talbert

79. Adrenal Gland Disorders
John G. Gums and Shawn Anderson

80. Pituitary Gland Disorders
Amy Heck Sheehan, Jack A. Yanovski, and Karim Anton Calis

SECTION 9
Gynecologic Disorders
Section Editor: Barbara G. Wells

81. Pregnancy and Lactation: Therapeutic Considerations
Denise L. Walbrandt Pigarelli, Connie K. Kraus, and Beth E. Potter

82. Contraception
Lori M. Dickerson, Sarah P. Shrader, and Vanessa A. Diaz

83. Menstruation-Related Disorders
Elena M. Umland, Lara C. Weinstein, and Edward Buchanan

84. Endometriosis
Deborah A. Sturpe

85. Hormone Therapy in Women
Sophia N. Kalantaridou, Susan R. Davis, and Karim Anton Calis

SECTION 10
Urologic Disorders
Section Editor: L. Michael Posey

86. Erectile Dysfunction
Mary Lee

87. Management of Benign Prostatic Hyperplasia
Mary Lee

88. Urinary Incontinence
Eric S. Rovner, Jean Wyman, Thomas Lackner, and David Guay

SECTION 11
Immunologic Disorders
Section Editor: Gary C. Yee

89. Function and Evaluation of the Immune System
Philip D. Hall and Nicole A. Weimert

90. Systemic Lupus Erythematosus and Other Collagen-Vascular Diseases
1431 Jeffrey C. Delafuente and Kimberly A. Cappuzzo

91. Allergic and Pseudoallergic Drug Reactions
Joseph T. DiPiro

92. Solid-Organ Transplantation
Kristine S. Schonder and Heather J. Johnson

SECTION 12
Rheumatologic Disorders
Section Editor: L. Michael Posey

93. Osteoporosis and Other Metabolic Bone Diseases
Mary Beth O’Connell and Sheryl F. Vondracek

94. Rheumatoid Arthritis
Arthur A. Schuna

95. Osteoarthritis
Lucinda M. Buys and Mary Elizabeth Elliott

96. Gout and Hyperuricemia
Michael E. Ernst, Elizabeth C. Clark, and David W. Hawkins

SECTION 13
Ophthalmic and Otolaryngologic Disorders
Section Editor: L. Michael Posey

97. Glaucoma
Richard G. Fiscella, Timothy S. Lesar, and Deepak P. Edward

98. Allergic Rhinitis
J. Russell May and Philip H. Smith

SECTION 14
Dermatologic Disorders
Section Editor: L. Michael Posey

99. Dermatologic Drug Reactions and Self-Treatable Skin Disorders
Nina H. Cheigh

100. Acne Vulgaris
Dennis P. West, Amy Loyd, Kimberly A. Bauer, Lee E. West, Laura Scuderi, and Giuseppe Micali

101. Psoriasis
Dennis P. West, Amy Loyd, Lee E. West, Kimberly A. Bauer, Maria Letizia Musumeci, and Giuseppe Micali

102. Atopic Dermatitis
Nina H. Cheigh

SECTION 15
Hematologic Disorders
Section Editor: Gary C. Yee

103. Hematopoiesis
William P. Petros and Michael Craig

104. Anemias
Beata A. Ineck, Barbara J. Mason, and William L. Lyons

105. Coagulation Disorders
Betsy Bickert Poon and Char Witmer

106. Sickle Cell Anemia
C. Y. Jennifer Chan and Reginald H. Moore

107. Drug-Induced Hematologic Disorders
Dale H. Whitby and Thomas E. Johns

SECTION 16
Infectious Diseases
Section Editor: Joseph T. DiPiro

108. Laboratory Tests to Direct Antimicrobial Pharmacotherapy
Michael J. Rybak and Jeffrey R. Aeschlimann

109. Antimicrobial Regimen Selection
David S. Burgess

110. Central Nervous System Infections
Isaac F. Mitropoulos, Elizabeth D. Hermsen, Jeremy A. Schafer, and John C. Rotschafer

111. Lower Respiratory Tract Infections
Mark L. Glover and Michael D. Reed

112. Upper Respiratory Tract Infections
Yasmin Khaliq, Sarah Forgie, and George Zhanel

113. Influenza
Elizabeth D. Hermsen and Mark E. Rupp

114. Skin and Soft-Tissue Infections
Douglas N. Fish, Susan L. Pendland, and Larry H. Danziger

115. Infective Endocarditis
Michael A. Crouch and Angie Veverka

116. Tuberculosis
Charles A. Peloquin

117. Gastrointestinal Infections and
Enterotoxigenic Poisonings Steven Martin and Rose Jung

118. Intraabdominal Infections
Joseph T. DiPiro and Thomas R. Howdieshell

119. Parasitic Diseases
J. V. Anandan

120. Urinary Tract Infections and Prostatitis
Elizabeth A. Coyle and Randall A. Prince

121. Sexually Transmitted Diseases
Leroy C. Knodel

122. Bone and Joint Infections
Edward P. Armstrong and Allan D. Friedman

123. Sepsis and Septic Shock
S. Lena Kang-Birken and Joseph T. DiPiro

124. Superficial Fungal Infections
Thomas E. R. Brown and Thomas W. F. Chin

125. Invasive Fungal Infections
Peggy L. Carver

126. Infections in Immunocompromised Patients
Douglas N. Fish

127. Antimicrobial Prophylaxis in Surgery
Salmaan Kanji and John W. Devlin

128. Vaccines, Toxoids, and Other Immunobiologics
Mary S. Hayney

129. Human Immunodeficiency Virus Infection
Peter L. Anderson, Thomas N. Kakuda, and Courtney V. Fletcher

SECTION 17
Oncologic Disorders
Section Editor: Gary C. Yee

130. Cancer Treatment and Chemotherapy
Patrick J. Medina and Chris Fausel

131. Breast Cancer
Laura Boehnke Michaud, Janet L. Espirito, and Francisco J. Esteva

132. Lung Cancer
Jeannine S. McCune and Deborah A. Frieze

133. Colorectal Cancer
Patrick J. Medina, Weijing Sun, and Lisa E. Davis

134. Prostate Cancer
Jill M. Kolesar

135. Lymphomas
Val R. Adams and Gary C. Yee

136. Ovarian Cancer
Judith A. Smith and Judith K. Wolf

137. Acute Leukemias
Helen L. Leather and Betsy Bickert Poon

138. Chronic Leukemias
Amy M. Pick, Marcel Devetten, and Timothy R. McGuire

139. Multiple Myeloma
Timothy R. McGuire

140. Myelodysplastic Syndromes
Julianna A. Burzynski and Trevor McKibbin

141. Skin Cancer
Rowena N. Schwartz and Lindsay J. Corporon

142. Hematopoietic Stem Cell Transplantation
Janelle B. Perkins and Gary C. Yee

SECTION 18
Nutrition Disorders
Section Editor: Gary R. Matzke

143. Assessment of Nutrition Status and Nutrition Requirements
Katherine Hammond Chessman and Vanessa J. Kumpf

144. Prevalence and Significance of Malnutrition
Gordon Sacks and Catherine M. Crill

145. Parenteral Nutrition
Todd W. Mattox and Pamela D. Reiter

146. Enteral Nutrition
Vanessa J. Kumpf and Katherine Hammond Chessman

147. Nutritional Considerations in Major Organ Failure
Brian M. Hodges and Mark DeLegge

148. Obesity
John V. St. Peter and Charles J. Billington

Glossary
Index
Pharmacotherapy 7th Edition