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Chapter Outline
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  1. Introduction
    1. Psychophysiological disorders are illnesses influenced by emotional factors
      1. Widely diverse medical conditions are affects, if not caused by psychological factors
      2. DSM-IV and DSM-IV-TR have a comprehensive category that may be applied to any illness
      3. Researchers recognize that physically caused illness can cause stress, which affects course of illness
    2. Health psychology reflects holistic concept of body and mind
  2. Mind and Body
    1. Mind/Body Problem
      1. Refers to question of relationship between mind and body
    2. Historically, mind and body were seen as separate, as in dualism
      1. Plato originated idea
      2. Laid foundation of modern science rationalism; nature explained through empirical evidence
      3. Organic causation was the rule in explaining illness
      4. Once thought involuntary, physiological functions could be influenced voluntarily
      5. Mind and body are one; psychological and physical refer to different ways of talking about same phenomenon
    3. Psychological Stress
      1. Defining Stress
        1. Stress can be defined as a stimulus: stress consists of environmental demands that lead to physical responses
        2. Stress can be defined as response; general adaptation syndrome with three stages
        3. Stress can be defined as interaction between stimulus and person's appraisal of it
      2. What Determines Responses to Stress?
        1. Stimulus Specificity
          1. Stimulus specificity refers to different kinds of stress that produce different kinds of physiological responses
          2. Subtle distinctions can be made; reactions differ if we are expecting a stressful event or are undergoing the event
          3. Reactions are very complex since different stressors produce different patterns of responses
        2. Individual Response Specificity
          1. People have characteristic patterns of physiological response called individual response specificity
          2. Some people respond to stress more intensely
        3. Stimulus Versus Individual
          1. Person and stressor operate simultaneously
          2. Degree of increase and decrease subject to individual response specificity
    4. How Stress Influences Illness
      1. Connection exists between stress and illness
      2. Changes in Physiological Functioning
        1. Stress and the Autonomic Nervous System
          1. ANS controls smooth muscles, glands, and internal organs
          2. Sympathetic division mobilizes body; parasympathetic division returns body to resting state
          3. ANS contributes to fight-or-flight response
        2. Changes in the Immune System
          1. Immune system is body's system of defense against infectious disease and cancer
          2. Psychoneuroimmunology is the study of the immune system's link between stress and illness
          3. Studying subjects following naturalistic major events, minor events, and laboratory stressors suggests decreases in cellular immunity and reduced immune functioning
        3. Feedback Loops
          1. Body systems provide feedback or information about relating the system
          2. Negative feedback is important in theories of stress and illness
          3. Disregulation model argues that stress-related illness occurs when there is disruption in negative feedback
          4. Oscillations are rhythmic back-and-forth cycle of body systems
          5. Stress may disrupt rhythms affecting other systems
      3. Changes in High-Risk Behavior
        1. Stress may cause people to adopt behavior that puts them at risk of illness
        2. Stress can interfere with preventive measure against disease
        3. Stress may encourage its victims to report illness
  3. Psychological Factors and Physical Disorders
    1. Coronary Heart Disease (CHD)
      1. Coronary heart disease (CHD) caused by atherosclerosis and manifested as heart attack or sudden cardiac death
      2. A number of risk factors have been identified
      3. Link exists between social environment/status and atherosclerosis
      4. Relationship between social and occupational stress and development and progression of coronary heart disease
      5. Cardiovascular reactivity thought to contribute to development and expression of coronary heart disease
      6. Research suggests relationship between some qualities (e.g., hostility, anger) seen in Type A people and heart disease
    2. Hypertension
      1. Chronically high blood pressure is known as hypertension
      2. Hypertension increases risk for other cardiovascular disorders
      3. The regulatory mechanism involving feedback breaks down and blood vessels remain chronically constricted
      4. Essential hypertension occurs where there is no known organic cause
        1. Hypertensives may live in environments where stimuli that increase blood pressure are common
        2. Individual response specificity may play role in essential hypertension
      5. Many people with hypertension are unaware of the condition
    3. Cancer
      1. Cancer is associated with psychological stress
      2. Social support and group therapy help patients with breast cancer and malignant melanoma
      3. Active coping may be a benefit of group therapy
    4. AIDS
      1. Acquired immune deficiency syndrome (AIDS) is caused by the human immunodeficiency virus (HIV)
      2. Virus, found in several bodily fluids, attacks the immune system, leaving the person open to various infections (e.g., Kaposi's sarcoma)
      3. The relationship between stress and the course of AIDS is unclear
      4. Avoidance behavior has been seen as a benefit of psychological treatment
    5. Headache
      1. Migraine headaches and muscle-contraction headaches are related to stress but differ from each other in several ways
      2. Theories of migraine have shifted away from psychological to organic causes
        1. Involves dysfunction in operation of serotonin
        2. Precise nature of serotonin dysfunction is not known
        3. Genetic, hormonal factors may play role
        4. Stress can trigger migraine headache
    6. Obesity
      1. Eating behavior can be affected by disruption in the normal regulatory cycle
      2. Anorexia nervosa is extreme malnourishment
      3. Obesity, as a socially defined condition, refers to an excessive amount of fat on the body
      4. Physical and social consequences of obesity
      5. Genetic differences and behavioral differences contribute to obesity
      6. Obesity also due to interaction of physiological and psychological factors such as more responsiveness to taste of food and problem of feedback from stomach to brain
      7. Weight-loss programs shifting emphasis from dieting to exercise
      8. Most effective programs focus on several components
      9. Some have argued for a more broad definition of physical attractiveness
    7. Sleep Disorders
      1. Insomnia
        1. Insomnia is the chronic inability to sleep
        2. There are three broad patterns of insomnia--problems with falling asleep, awakening repeatedly during night, waking up too early
        3. Concern for sleep disturbance leads to anticipatory anxiety
        4. Many factors are related to insomnia such as drugs, alcohol, and stress
        5. The definition of sleep affects whether insomniacs are actually sleeping
        6. Hypnotics are used, which cause several problems
          1. Altering architecture of sleep leading to REM rebound
          2. Withdrawal from drug leads to insomnia
        7. An illegal market for benzodiazepines has emerged
        8. A new hypnotic may be promising, with fewer side effects
        9. Most hypnotics are not effective over the long term
      2. Circadian Rhythm Disorders
        1. Circadian rhythm disorders occur when people try to sleep at times that are inconsistent with their circadian rhythms
        2. Common among shift workers but not limited to them
        3. Target bedtime and light therapy appear to be effective treatments
  4. Groups at Risk
    1. Gender
      1. Risk for coronary heart disease is higher among men
        1. May be due to reproductive hormones
        2. May be due to men more likely to engage in potentially health-damaging behaviors
      2. Others suggest gender differences in experience of stressors
    2. Race
      1. African-Americans have higher rates for hypertension, as well as morbidity and mortality rates for several disorders
      2. Data on racial differences in cardiovascular disorders are unclear
      3. Socioeconomic status and race are related
    3. Socioeconomic Status (SES)
      1. Socioeconomic status is a factor in determining health
      2. Association may be function of greater emotional impact of stressful life events
      3. Socioeconomic status affects development and progression of coronary heart disease
      4. Work environment where there is low control over decisions and low skills requirements may be important
      5. A relationship may exist between survival and recovery and socioeconomic status
  5. Stress and Illness: Theory and Therapy
    1. The Behavioral Perspective
      1. Respondent versus Operant
        1. Respondent conditioning can have powerful effect on physiological responses
        2. Physiological responses (e.g., blood pressure, urine formation) can be modified by operant conditioning
          1. Learning could operate in development of physical disorders
          2. Learning can be used to relieve the disorder
      2. Biofeedback, Relaxation, and Exercise
        1. Biofeedback training can give patients ability to control physiological functions
        2. Patients given immediate feedback in biofeedback training
        3. Relaxation training used extensively in stress-relief programs; uses progressive relaxation
        4. Exercise may be effective in reducing stress
    2. The Cognitive Perspective
      1. Predictability and Control
        1. Predictable stimuli are less stressful than unpredictable stimuli
        2. Control helps to reduce stress
        3. Coping can solve problems that create stress; it can also affect our physiological response to stress
        4. Coping is connected to cognitive processes and is determined by cognitive styles
        5. Lazarus's model sees stress as a dynamic reciprocal, interactive relationship involving six basic factors
          1. Environmental event
          2. Primary appraisal of event
          3. Secondary appraisal
          4. Coping
          5. Outcomes of coping
          6. Health outcomes
      2. Stress Management Intervention
        1. Goal of stress-management programs is to pinpoint the sources of stress and to build skills to cope with stressors
        2. People taught muscle relaxation,
        3. Programs developed for Type A's, cardiac rehabilitation programs
        4. Cognitive-behavioral stress-management programs developed and include relaxation training, cognitive restructuring, assertiveness training, and health education
    3. The Psychodynamic Perspective
      1. Psychological Inhibition
        1. Refers to stress-related physical disorders such as organ neuroses
        2. Disorders caused by repression, anxiety, and defense
        3. Family interactions central to stress-related physical disorders
        4. Inhibition of expression of emotion, behavioral, and social impulses contributes to development of "psychosomatic" disorders
      2. The Value of Catharsis
        1. Research confirms value of emotional catharsis to physical health
        2. Journaling may have effect on immune system by allowing expression of negative emotion
    4. The Interpersonal Perspective
      1. Major source of physical illness is the stress imposed by modern industrial society
      2. No regular social support prevents protection against illness
      3. Strong evidence to show that people without social support are more prone to disease
      4. Marital status is a risk factor for physical illness
    5. The Sociocultural Perspective
      1. Changes in society affect susceptibility of certain groups to particular illnesses
      2. Gender and race are important risk factors
    6. The Neuroscience Perspective
      1. Genetic Predisposition
        1. Stress-related physical disorders tend to run in families
        2. Early identification of those at risk is important
      2. PNI and Interactive Theories
        1. Different perspectives represent differences of focus
        2. Stress and illness are interactive







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