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1 |  |  All known lineages of animals are related by descent from common ancestral groups. |
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 |  | A) | True |
 |  | B) | False |
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2 |  |  Genes, under the influence of environmental factors, guide the orderly sequence of differentiation of a fertilized egg into an adult organism. |
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 |  | A) | True |
 |  | B) | False |
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3 |  |  The first person to formulate the cardinal principles of heredity was... |
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 |  | A) | Oparin |
 |  | B) | Hemingway |
 |  | C) | Mendel |
 |  | D) | Paganini |
 |  | E) | Crick |
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4 |  |  Garden peas had advantages over other organismal systems for investigation of inheritance because they... |
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 |  | A) | Were available in pure strains |
 |  | B) | Were inexpensive |
 |  | C) | Were self-fertilizing but capable of cross-fertilization |
 |  | D) | Exhibit distinct traits |
 |  | E) | All of the above are correct |
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5 |  |  Which of the following is NOT correct about meiosis? |
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 |  | A) | Meiosis produces haploid gametes from diploid cells |
 |  | B) | Meiosis has one reductional division and two cytoplasmic divisions |
 |  | C) | Unlike mitosis, chromosomes are duplicated twice in interphase |
 |  | D) | In meiosis, homologous chromosomes meet in synapsis to form tetrads |
 |  | E) | All of the above are correct |
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6 |  |  Which of the following is NOT a method of sex determination system in animals? |
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 |  | A) | XX-XY system |
 |  | B) | XX-XO system |
 |  | C) | ZZ-ZW system |
 |  | D) | Sex system in which the environmental conditions produces different sexes |
 |  | E) | All of the above are systems for sex determination in animals |
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7 |  |  Which of the following is mismatched? |
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 |  | A) | Law of segregation-genes separate independently of one another during meiosis |
 |  | B) | Phenotype-the visible features of an organism |
 |  | C) | Genotype-the genetic constitution of an organism |
 |  | D) | Loci-a dominant gene |
 |  | E) | Monohybrid cross-a cross involving only one pair of contrasting traits |
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8 |  |  In a monohybrid cross of an individual with an AA genotype with another of aa genotype, the phenotypic ratio of the offspring would be: |
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 |  | A) | 100 percent dominant |
 |  | B) | 50 percent dominant; 50 percent recessive |
 |  | C) | 100 percent recessive |
 |  | D) | 75 percent dominant; 25 percent recessive |
 |  | E) | The answer cannot be determined from the information given |
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9 |  |  One way of determining if an individual is homozygous or heterozygous dominant for a particular trait is to conduct a testcross with that individual. |
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 |  | A) | True |
 |  | B) | False |
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10 |  |  Which of the following is true in a case of intermediate inheritance? |
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 |  | A) | Neither allele is completely dominant over the other |
 |  | B) | The heterozygote phenotype appears either intermediate between or distinct from those of the parent. |
 |  | C) | One allele is always dominant over the other |
 |  | D) | Both A and B are correct |
 |  | E) | None of the above is correct |
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11 |  |  Mendel's Second Law is known as the law of independent assortment, which states that genes located on different pairs of homologous chromosomes do NOT assort independently during meiosis. |
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 |  | A) | True |
 |  | B) | False |
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12 |  |  The probability of independent events occurring together involves the... |
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 |  | A) | Multiplication rule |
 |  | B) | Rule of independent assortment |
 |  | C) | Product rule |
 |  | D) | Rule of exponents |
 |  | E) | Rule of probability |
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13 |  |  Which of the following is incorrect? |
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 |  | A) | Polygenic inheritance-many different genotypes may affect a single phenotype |
 |  | B) | Pleiotropy-a single gene may influence the expression of multiple traits |
 |  | C) | Quantitative inheritance-continuous variation in phenotypes |
 |  | D) | Sex-linked inheritance-traits carried on somatic chromosomes |
 |  | E) | All of the above are correct |
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14 |  |  There should be as many linkage groups as there are chromosome pairs. |
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 |  | A) | True |
 |  | B) | False |
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15 |  |  The exchange of homologous sections of DNA between nonsister chromatids is called: |
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 |  | A) | Synaptonemal complex |
 |  | B) | Euploidy |
 |  | C) | Crossing over |
 |  | D) | Polyploidy |
 |  | E) | Genetic nondisjunction |
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16 |  |  Which of the following is NOT correct? |
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 |  | A) | Aneuploidy is usually caused by the failure of chromosomes to separate during meiosis. |
 |  | B) | Down syndrome is typically caused by trisomy 21 |
 |  | C) | A syndrome is a group of symptoms associated with a particular disease or abnormality |
 |  | D) | Inversion is where a portion of a chromosome is duplicated |
 |  | E) | Translocations is where nonhomologous chromosomes exchange sections |
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17 |  |  Beadle and Tatum are perhaps best known for their "one gene-one enzyme" hypothesis. |
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 |  | A) | True |
 |  | B) | False |
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18 |  |  Nucleic acids are composed of repeated units called nucleotides, each of which is composed of a five-carbon sugar, a nitrogenous base, and a protein. |
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 |  | A) | True |
 |  | B) | False |
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19 |  |  Which of the following is NOT correct? |
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 |  | A) | Pyrimidines include cytosine, thymine, and uracil |
 |  | B) | Purines include adenine and guanine |
 |  | C) | The 5' end of the DNA backbone has a free phosphate group on the 5' carbon of the ribose |
 |  | D) | The two DNA strands of the double helix run antiparallel to each other |
 |  | E) | All of the above are correct |
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20 |  |  Every time a cell divides, the structure of DNA must be precisely copied in the daughter cells in a process called: |
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 |  | A) | Replication |
 |  | B) | Templation |
 |  | C) | Complementation |
 |  | D) | Sequencing |
 |  | E) | None of the above is correct |
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21 |  |  A codon is composed of three nucleotides and there are 64 possible codons in RNA. |
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 |  | A) | True |
 |  | B) | False |
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22 |  |  DNA is remarkably stable; in fact, various types of damage and repair are known, such as... |
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 |  | A) | Deletion repair |
 |  | B) | Addition repair |
 |  | C) | Translocation repair |
 |  | D) | Ligase repair |
 |  | E) | Excision repair |
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23 |  |  Ribosomal, transfer, and messenger RNAs are transcribed directly from DNA, each encoded by different sets of genes, a process requiring DNA polymerase. |
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 |  | A) | True |
 |  | B) | False |
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24 |  |  Genes are composed of intervening segments called introns, and exons that translated into protein. |
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 |  | A) | True |
 |  | B) | False |
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25 |  |  Which of the following is NOT correct? |
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 |  | A) | In mammals, genes coding for histones and interferons are on continuous stretches of DNA |
 |  | B) | Genes coding for many proteins are split |
 |  | C) | The process of translation takes place on the mitochondria |
 |  | D) | Transfer RNA collect free amino acids from the cytoplasm and deliver them to the polysome |
 |  | E) | All of the above are correct |
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26 |  |  Transfer RNA has a sequence of three bases called the anticodon that forms base pairs with complementary bases on the messenger RNA. |
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 |  | A) | True |
 |  | B) | False |
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27 |  |  Which of the following is NOT a form of gene regulation in eukaryotes? |
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 |  | A) | Transcriptional control |
 |  | B) | Translational control |
 |  | C) | Gene rearrangement |
 |  | D) | DNA modification |
 |  | E) | All of the above are forms of gene regulation in eukaryotes |
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28 |  |  Which of the following statements is NOT correct? |
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 |  | A) | Recombinant DNA tools-restriction endonucleases |
 |  | B) | DNA Ligase-seals complementary base pairs |
 |  | C) | Recombinant DNA-DNA from two different sources |
 |  | D) | PCR-polymerase chain reaction |
 |  | E) | All of the above are correct |
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29 |  |  The scientific field of mapping, sequencing, and analyzing genomes is known as... |
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 |  | A) | Genomics |
 |  | B) | Proteomics |
 |  | C) | Euchromatomics |
 |  | D) | RFLP analysis |
 |  | E) | None of the above is correct |
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30 |  |  Sources of phenotypic variation include which of the following? |
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 |  | A) | The independent assortment of chromosomes during meiosis |
 |  | B) | Crossing over during meiosis |
 |  | C) | Random fusion of gametes |
 |  | D) | Gene mutations |
 |  | E) | All of the above can provide sources for phenotypic variation |
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31 |  |  Although mutation occurs randomly, different mutation rates prevail at different loci. |
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 |  | A) | True |
 |  | B) | False |
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32 |  |  The crucial defect in cancer cells is that they proliferate in an unrestrained manner. This is called: |
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 |  | A) | Neoplastic growth |
 |  | B) | Oncogenetic suppression |
 |  | C) | Benign tumor growth |
 |  | D) | Ras proliferation |
 |  | E) | None of the above is correct |
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33 |  |  In their normal form, oncogenes are called proto-oncogenes. One such proto-oncogene codes for a protein called Ras, which is activated, initiates a cascade of reactions that leads to cell division. |
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 |  | A) | True |
 |  | B) | False |