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| 1 |  |  The fibrous protein ____________ imparts the stratum corneum with strength and water resistance. |
|  | A) | collagen |
|  | B) | elastin |
|  | C) | keratin |
|  | D) | eleidin |
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| 2 |  |  If you stepped on a nail, the second epidermal layer it would penetrate is the stratum |
|  | A) | lucidum |
|  | B) | corneum |
|  | C) | spinosum |
|  | D) | granulosum |
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| 3 |  |  The most superficial sensory receptors in the skin are called |
|  | A) | Merkel cells |
|  | B) | epidermal dendritic cells |
|  | C) | tactile corpuscles |
|  | D) | lamellated corpuscles |
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| 4 |  |  A person with defective ____________ would be particularly at risk for both infection and cancer in the deeper epidermal layers. |
|  | A) | stem cells |
|  | B) | Langerhans cells |
|  | C) | Merkel cells |
|  | D) | melanocytes |
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| 5 |  |  The connective tissue component of the cutaneous membrane is otherwise known as the ____________. |
|  | A) | stratum corneum |
|  | B) | stratum basale |
|  | C) | epidermis |
|  | D) | dermis |
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| 6 |  |  Which of the following is false? Ceruminous glands |
|  | A) | produce earwax in the external ear canal |
|  | B) | are modified sebaceous glands |
|  | C) | are much less numerous than eccrine glands |
|  | D) | are related to glands that help to regulate body temperature |
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| 7 |  |  A result of skin exposure to UV radiation that actually promotes good health is |
|  | A) | synthesis of cholecalciferol |
|  | B) | decreased melanocyte activity |
|  | C) | mild sunburn to promote replacement of old epidermal cells |
|  | D) | a deep bronze tan |
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| 8 |  |  Apocrine sweat glands, variously modified, serve the reproductive system through their secretion of |
|  | A) | sex hormones |
|  | B) | milk and pheromones |
|  | C) | both a and b |
|  | D) | neither a nor b |
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| 9 |  |  Of the following, the least specific skin problem is |
|  | A) | psoriasis |
|  | B) | folliculitis |
|  | C) | impetigo |
|  | D) | pruritis |
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| 10 |  |  All of the following conditions directly involve sebaceous glands except |
|  | A) | urticaria |
|  | B) | acne |
|  | C) | furuncles |
|  | D) | folliculitis |
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| 11 |  |  The following statements all characterize basal cell carcinomas. Which one does not apply equally well to other forms of skin cancer? |
|  | A) | they originate deep in the epidermis |
|  | B) | they seldom metastasize to other tissues |
|  | C) | they are strongly linked to previous damage by UV radiation |
|  | D) | they are the result of uncontrolled mitosis |
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| 12 |  |  Which of the following nail disorders might also be a symptom of kidney failure? |
|  | A) | onychomycosis |
|  | B) | yellow nail syndrome |
|  | C) | half-and-half |
|  | D) | vertical ridging |
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| 13 |  |  Second-degree burns |
|  | A) | may cause slight scarring |
|  | B) | involve the epidermis and part of the dermis |
|  | C) | cause blistering beneath the epidermis |
|  | D) | all of the above |
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| 14 |  |  The skin turns red when a fair-skinned person blushes because |
|  | A) | carotenes become more prominent as the skin's temperature rises |
|  | B) | melanocytes are temporarily activated |
|  | C) | blood flow to the skin increases |
|  | D) | blood flow to the skin decreases |
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| 15 |  |  Generally, a "bald" man has not really lost his hair but rather has replaced his ____________ hairs with ____________ hairs. |
|  | A) | vellus; lanugo |
|  | B) | terminal; vellus |
|  | C) | terminal; lanugo |
|  | D) | lanugo; terminal |
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| 16 |  |  The prevalence of acne during teenage years indicates that |
|  | A) | sex hormones trigger increased activity in sebaceous glands as well as other tissues |
|  | B) | teenagers do not care for their skin as well as older or younger individuals |
|  | C) | both of the above |
|  | D) | neither a nor b is correct |
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| 17 |  |  Systemic acne treatments (taken internally) potentially have much more widespread, sometimes unanticipated, effects than topical treatments. For example, ____________ and other systemic retinoids may be powerful teratogens. |
|  | A) | Retin-A |
|  | B) | Accutane |
|  | C) | salicylic acid |
|  | D) | doxycycline |
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| 18 |  |  Which type of acne lesion would be least responsive to antibiotic treatment? |
|  | A) | comedo |
|  | B) | papule |
|  | C) | nodule |
|  | D) | cyst |
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| 19 |  |  In which layers of the epidermis would you find mitotically active cells? |
|  | A) | strata basale and spinosum |
|  | B) | strata granulosum and corneum |
|  | C) | strata granulosum and lucidum |
|  | D) | strata lucidum and corneum |
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| 20 |  |  Lanolin, refined from the lipid secretions of sheep skin, is often used to augment humans' holocrine skin secretion called |
|  | A) | cerumen |
|  | B) | sebum |
|  | C) | sweat |
|  | D) | none of the above |
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| 21 |  |  Which of the following are benign tumors that affect the appearance of the skin? |
|  | A) | capillary hemangiomas |
|  | B) | port-wine stains |
|  | C) | nevi |
|  | D) | all of the above |
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| 22 |  |  A genetic mutation preventing the production of the enzyme tyrosinase would result in the condition known as |
|  | A) | eczema |
|  | B) | alopecia |
|  | C) | albinism |
|  | D) | hemophilia |
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| 23 |  |  The most dangerous kind of skin cancer originates from |
|  | A) | melanocytes in an existing mole |
|  | B) | keratinocytes in the stratum basale |
|  | C) | keratinocytes in the stratum spinosum |
|  | D) | none of the above |
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| 24 |  |  Which skin color abnormalities result from alterations in blood contents rather than blood flow? |
|  | A) | pallor and erythema |
|  | B) | cyanosis and jaundice |
|  | C) | both a and b |
|  | D) | neither a nor b |
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| 25 |  |  A victim of extensive third-degree burns is at high risk not only from bacterial infection but also potentially lethal |
|  | A) | erythema |
|  | B) | scarring |
|  | C) | dehydration |
|  | D) | all of the above |
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