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Difficult Multiple Choice
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1
Which of the following tissues is found in the fewest body locations?
A)fibrocartilage
B)elastic cartilage
C)cortical bone
D)trabecular bone
2
During early embryonic development, cartilage grows both internally and along its periphery. The former is called ____________ growth; the latter, ____________.
A)appositional; interstitial
B)interstitial; appositional
C)osteogenic; chondrogenic
D)chondrogenic; osteogenic
3
One of the main differences between the two growth patterns of cartilage is the source of new
A)chondroblasts
B)chondrocytes
C)cartilage matrix
D)perichondrium
4
Why does all growth normally cease in mature cartilage?
A)the matrix of mature cartilage is not able to expand
B)cartilage has no blood supply and thus no energy source for growth
C)once mature, cartilage is converted to bone by endochondral ossification
D)both a and b
5
Chondrocytes die and stem cells in the perichondrium form osteoblasts during which of these processes?
A)appositional growth of cartilage
B)interstitial growth of bone
C)intramembranous ossification
D)endochondral ossification
6
Calcification occurs in ____________ during dermal ossification but in ____________ during endochondral ossification.
A)the dermis; hyaline cartilage
B)mesenchyme; fibrocartilage
C)osteoid; hyaline cartilage
D)osteoid; fibrocartilage
7
A layer of dense irregular connective tissue typically covers all of the following except
A)hyaline cartilage
B)fibrocartilage
C)elastic cartilage
D)compact bone
8
Which of the following is not a function of periosteum?
A)anchors blood vessels and nerves to the surface of the bone
B)isolates and protects the bone from surrounding structures
C)provides a smooth surface for articulation between bones
D)participates in appositional bone growth and fracture repair
9
Osteons are to dense bone as ____________ are to cancellous bone.
A)trabeculae
B)interstitial lamellae
C)parallel lamellae
D)canaliculi
10
By interconnecting the lacunae and the blood supply, ____________ allow osteocytes to transfer nutrients and wastes through an otherwise impenetrable solid matrix.
A)perforating canals
B)canaliculi
C)central canals
D)lamellae
11
Arrange the following from lowest to highest in terms of their contribution to the mass of bone tissue: (1) collagen fibers; (2) osteocytes, osteoblasts, and osteoclasts; and (3) calcium phosphate.
A)1, 2, 3
B)3, 1, 2
C)2, 1, 3
D)2, 3, 1
12
What change in physical structure would result from an excess of organic components relative to the amount of hydroxyapatite in the matrix of a bone?
A)greater rigidity
B)greater strength
C)decreased flexibility
D)increased flexibility
13
A major difference between compact and spongy bone is that
A)spongy bone forms only from mesenchyme
B)there are no osteons in spongy bone
C)spongy bone contains no hydroxyapatite
D)the trabeculae of compact bone are larger
14
During bone remodeling, if the rate of osteolysis exceeds the rate of osteogenesis, the bone becomes
A)longer and thinner
B)thicker along the shaft
C)demineralized
D)stronger
15
Under what circumstances does fibrocartilage normally ossify?
A)endochondral ossification
B)fracture repair
C)lamellar bone formation
D)interstitial growth
16
While eating fried chicken from a popular chain restaurant, David notices that the ends of the bones in the wing and drumstick are smooth, featureless, and covered with a thick cap of cartilage. What is the most likely explanation?
A)articular cartilage is much thicker in chickens than in humans
B)bird bones have completely different features from human bones
C)the chicken was so young that the bones were not fully ossified
D)none of the above
17
Lengthwise bone growth involves the final steps of
A)osteoporosis and osteopenia
B)fracture healing
C)intramembranous ossification
D)endochondral ossification
18
In interstitial bone growth, what happens when the zone of ossification overtakes the zone of resting cartilage?
A)the epiphyseal plate becomes the epiphyseal line
B)lengthwise growth of the bone terminates (at least at one end)
C)the metaphysis converts from hyaline cartilage to bone
D)all of the above
19
____________ is a continual, hormonally controlled process that is essentially a race between osteoblasts and osteoclasts.
A)appositional growth
B)interstitial growth
C)bone remodeling
D)endochondral ossification
20
Which types of fractures are inherently more likely in children than in adults?
A)epiphyseal and greenstick
B)transverse and comminuted
C)Colles and spiral
D)open and closed
21
The inadequate mineral deposition in bone caused by a vitamin D deficiency during childhood is called
A)scurvy
B)rickets
C)osteomyelitis
D)osteomalacia
22
The two hormones that have opposite effects on the rate of osteolysis are
A)somatotropin and somatomedin
B)growth hormone and thyroid hormone
C)parathyroid hormone and calcitonin
D)estrogen and testosterone
23
Ironically, high levels of ____________ at puberty not only accelerate lengthwise bone growth but also trigger its ultimate end.
A)sex hormones
B)thyroid gland hormones
C)anterior pituitary gland hormones
D)parathyroid hormone and somatomedin
24
Arrange the following in order of the average age at which they complete ossification, from youngest to oldest: (1) clavicle; (2) lateral epicondyle of humerus; and (3) proximal radius.
A)1, 2, 3
B)2, 3, 1
C)3, 1, 2
D)3, 2, 1
25
Osteopenia and ____________ both reduce bone mass, but the former is a normal part of aging whereas the latter is a disease.
A)osteomalacia
B)osteomyelitis
C)hyperostosis
D)osteoporosis







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