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alveolar ventilation (VA)  the volume of gas that reaches the alveolar region of the lung.
alveoli  microscopic air sacs located in the lung where gas exchange occurs between respiratory gases and the blood.
anatomical dead space  the total volume of the lung (i.e., conducting airways) that does not participate in gas exchange.
aortic bodies  receptors located in the arch of the aorta that are capable of detecting changes in arterial PO2.
Bohr effect  the right shift of the oxyhemoglobin dissociation curve due to a decrease of blood pH. Results in a decreased affinity for oxygen.
bulk flow  mass movement of molecules from an area of high pressure to an area of lower pressure.
carotid bodies  chemoreceptors located in the internal carotid artery; respond to changes in arterial PO2, PCO2, and pH.
cellular respiration  process of oxygen consumption and carbon dioxide production in cells (i.e., bioenergetics).
deoxyhemoglobin  hemoglobin not in combination with oxygen.
diaphragm  the major respiratory muscle responsible for inspiration. Dome-shaped--separates the thoracic cavity from the abdominal cavity.
diffusion  random movement of molecules from an area of high concentration to an area of low concentration.
hemoglobin  a heme-containing protein in red blood cells that is responsible for transporting oxygen to tissues. Hemoglobin also serves as a weak buffer within red blood cells.
myoglobin  protein in muscle that can bind oxygen and release it at low PO2 values; aids in diffusion of oxygen from capillary to mitochondria.
oxyhemoglobin  hemoglobin combined with oxygen; 1.34 ml of oxygen can combine with 1 g Hb.
partial pressure  the fractional part of the barometric pressure due to the presence of a single gas, e.g., PO2, PCO2, and PN2.
pleura  a thin lining of cells that is attached to the inside of the chest wall and to the lung; the cells secrete a fluid that facilitates the movements of the lungs in the thoracic cavity.
pulmonary respiration  term that refers to ventilation (breathing) of the lung.
residual volume (RV)  volume of air in the lungs following a maximal expiration.
respiration  external respiration is the exchange of oxygen and carbon dioxide between the lungs and the environment; internal respiration describes the use of oxygen by the cell (mitochondria).
spirometry  measurement of various lung volumes.
tidal volume  volume of air inhaled or exhaled in a single breath.
total lung capacity (TLC)  the total volume of air the lung can contain; equal to the sum of the vital capacity and the residual volume.
ventilation  the movement of air into or out of the lungs (e.g., pulmonary or alveolar ventilation); external respiration.
ventilatory threshold (Tvent)  the "breakpoint'' at which pulmonary ventilation and carbon dioxide output begin to increase exponentially during an incremental exercise test.
vital capacity (VC)  the volume of air that can be moved into or out of the lungs in one breath; equal to the sum of the inspiratory and expiratory reserve volumes and the tidal volume.







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