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actin  a structural protein of muscle that works with myosin in permitting muscular contraction.
concentric action  occurs when a muscle is activated and shortens.
dynamic  refers to an isotonic muscle action.
eccentric action  occurs when a muscle is activated and force is produced but the muscle lengthens.
endomysium  the inner layer of connective tissue surrounding a muscle fiber.
end-plate potential (EPP)  depolarization of a membrane region by a sodium influx.
epimysium  the outer layer of connective tissue surrounding muscle.
extensors  muscles that extend a limb--that is, increase the angle at a joint.
fasciculi  a small bundle of muscle fibers.
fast-twitch fibers  one of several types of muscle fibers found in skeletal muscle; also called Type II fibers; characterized as having low oxidative capacity but high glycolytic capacity.
flexors  muscle groups that cause flexion of limbs--that is, decrease the angle at a joint.
Golgi tendon organ (GTOs)  a tension receptor located in series with skeletal muscle.
intermediate fibers  muscle fiber type that generates high force at a moderately fast speed of contraction, but has a relatively large number of mitochondria (Type IIa).
isometric  action in which the muscle develops tension, but does not shorten; also called a static contraction. No movement occurs.
lateral sac  see terminal cisternae.
motor neurons  efferent neurons that conduct action potentials from the central nervous system to the muscles.
motor unit  a motor neuron and all the muscle fibers innervated by that single motor neuron; responds in an "all-or-none" manner to a stimulus.
muscle action  term used to describe muscle form development.
muscle spindle  a muscle stretch receptor oriented parallel to skeletal muscle fibers; the capsule portion is surrounded by afferent fibers, and intrafusal muscle fibers can alter the length of the capsule during muscle contraction and relaxation.
myofibrils  the portion of the muscle containing the thick and thin contractile filaments; a series of sarcomeres where the repeating pattern of the contractile proteins gives the striated appearance to skeletal muscle.
myosin  contractile protein in the thick filament of a myofibril that contains the cross-bridge that can bind actin and split ATP to cause tension development.
neuromuscular junction  synapse between axon terminal of a motor neuron and the motor end plate of a muscle's plasma membrane.
perimysium  the connective tissue surrounding the fasciculus of skeletal muscle fibers.
sarcolemma  the cell (plasma) membrane surrounding a muscle fiber.
sarcomeres  the repeating contractile unit in a myofibril bounded by Z-lines.
sarcoplasmic reticulum  a membranous structure that surrounds the myofibrils of muscle cells; location of the terminal cisternae or lateral sacs that store the Ca11 needed for muscle contraction.
sliding filament model  a theory of muscle contraction describing the sliding of the thin filaments (actin) past the thick filaments (myosin).
slow-twitch fibers  muscle fiber type that contracts slowly and develops relatively low tension but displays great endurance to repeated stimulation; contains many mitochondria, capillaries, and myoglobin.
summation  repeated stimulation of a muscle that leads to an increase in tension compared to a single twitch.
terminal cisternae  portion of the sarcoplasmic reticulum near the transverse tubule containing the Ca11 that is released upon depolarization of the muscle; also called lateral sac.
tetanus  highest tension developed by a muscle in response to a high frequency of stimulation.
transverse tubule  an extension, invagination, of the muscle membrane that conducts the action potential into the muscle to depolarize the terminal cisternae, which contain the Ca11 needed for muscle contraction.
tropomyosin  protein covering the actin binding sites that prevents the myosin cross-bridge from touching actin.
troponin  protein, associated with actin and tropomyosin, that binds Ca11 and initiates the movement of tropomyosin on actin to allow the myosin cross-bridge to touch actin and initiate contraction.
twitch  the tension-generating response following the application of a single stimulus to muscle.
Type I fibers  fibers that contain large numbers of oxidative enzymes and are highly fatigue resistant.
Type IIa fibers  fibers that contain biochemical and fatigue characteristics that are between Type IIb and Type I fibers.
Type IIb fibers  fibers that have a relatively small number of mitochondria, a limited capacity for aerobic metabolism, and are less resistant to fatigue than slow fibers.







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