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Multiple Choice Quiz
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1

Proteomics
A)is another term for genomics in humans.
B)is the study of the collection of proteins produced in a particular cell.
C)is the study of proteins produced by a particular gene.
D)proves that a single gene codes for only one protein.
2

The composition of human hemoglobin
A)remains constant throughout the lifetime of an individual.
B)is the same in the embryonic and adult forms.
C)always contains two copies of two different subunits.
D)decreases in the amount of beta chain as the individual ages.
3

The histone code refers to the
A)pattern of histone binding to chromosomes.
B)amino acid sequence found in all histones.
C)length of the histones.
D)three nucleotides that determine an amino acid.
4

Small interfering RNAs are capable of
A)being translated.
B)interfering with transcription.
C)leading to the destruction of certain mRNAs.
D)cutting up other RNAs.
5

In humans, there are many fewer genes than there are different proteins produced. This is primarily due to
A)combining different combinations of introns together.
B)small interfering RNAs.
C)the histone code.
D)exon shuffling.
6

Introns for one gene may contain parts of another gene.
A)True
B)False
C)This has not yet been seen
7

Ribosomal RNAs are cut to their final size by
A)tRNAs.
B)other rRNAs.
C)mRNAs.
D)snoRNAs.
8

The most abundant type of repeated DNA sequence is
A)transposons.
B)pseudogenes.
C)centromeres.
D)telomeres.
9

Trans-splicing refers to
A)post-splicing modifications of the RNA.
B)splicing of RNAs that leads to exon shuffling.
C)the process that produces RNAs with instructions from both strands of a gene.
D)when one precursor protein is cut to yield two different proteins.
10

The enzyme dicer is responsible for
A)repair of mistakes made in DNA replication.
B)cutting double-stranded RNAs into short pieces.
C)unwinding double-stranded RNAs.
D)transposition of certain transposons.
11

Researchers have used RNAi to
A)decrease gene expression of the virus that causes SARS.
B)make decaffeinated coffee taste better.
C)analyze the role of various genes in the nematode worm Caenorhabditis elegans.
D)all of the above.
12

Which statement about pancreatic hormones is not true?
A)The endocrine hormones are secreted from a single cell type.
B)The most abundant endocrine cell secretes insulin.
C)Exocrine and endocrine cells derive from a single stem cell type.
D)Glucagon is one of the hormones secreted by endocrine cells.
13

The enhanceosome
A)binds to the TATA box to enhance transcription.
B)adds methyl groups to DNA.
C)turns transcription off.
D)binds to an acetylase enzyme.
14

There are both post-transcriptional and post-translational processes that account for so many proteins being produced from so few genes in humans. An example of a post-translational process is
A)exon shuffling.
B)trans-splicing.
C)the cutting of a precursor protein to yield two or more final proteins.
D)RNA interference.
15

Which statement is true about Alu repeats?
A)The number of Alu repeats has remained constant throughout the history of mankind.
B)There may be as many as 500,000 per genome.
C)They are classified as long interspersed elements.
D)Alu repeats make up as much as 25% of the genome.
16

Pseudogenes
A)lead to the production of proteins that have no function.
B)may be copies of genes that are no longer used.
C)are transcribed into snoRNAs.
D)are very rare in the human genome.
17

Genes for tRNA
A)make up about 10% of our genome.
B)are scattered randomly around the human genome.
C)are more abundant in the frog genome.
D)are all transcribed equally in all cell types.
18

If we look at the relative abundances of different categories of proteins, as we move from the prenatal period to birth and old age,
A)the relative expression of transcription factors decreases.
B)the relative expression of enzymes decreases.
C)the relative expression of transcription factors increases.
D)the relative expression of enzymes remains the same.
19

Fetal hemoglobin
A)carries less oxygen than adult hemoglobin.
B)consists mainly of beta chains.
C)still makes up a substantial percentage of all hemoglobin at birth.
D)differs from adult hemoglobin by the presence of the zeta chain.
20

Chromatin remodeling
A)can turn on transcription but cannot silence genes.
B)can be inherited.
C)involves only the addition of methyl groups to DNA.
D)requires RNAi.





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