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| 1 |  |  When an enzyme catalyzes a chemical reaction some of the enzyme is lost. |
|  | A) | True |
|  | B) | False |
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| 2 |  |  The amount of energy released by a chemical reaction is much greater when an enzyme catalyzes it. |
|  | A) | True |
|  | B) | False |
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| 3 |  |  An enzyme works by decreasing the activation energy of a chemical reaction. |
|  | A) | True |
|  | B) | False |
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| 4 |  |  The chemical reactions of living cells could not occur in the absence of enzymes. |
|  | A) | True |
|  | B) | False |
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| 5 |  |  A substrate molecule binds to certain amino acids that line the active site of an enzyme. |
|  | A) | True |
|  | B) | False |
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| 6 |  |  Hydrolases are enzymes that remove water from organic molecules (that is, remove -H and -OH chemical groups and produce water as a reaction product, known as dehydration). |
|  | A) | True |
|  | B) | False |
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| 7 |  |  All enzyme names end with the suffix -ase. |
|  | A) | True |
|  | B) | False |
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| 8 |  |  Enzymes increase the energy content of the reactants (or substrates). |
|  | A) | True |
|  | B) | False |
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| 9 |  |  One reason enzymes are so effective is that each enzyme can catalyze a broad range of metabolic reactions. |
|  | A) | True |
|  | B) | False |
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| 10 |  |  Isoenzymes are enzymes that perform the same function in different cells and have slightly different chemical structures. |
|  | A) | True |
|  | B) | False |
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| 11 |  |  The active sites of isoenzymes are not affected by the structural differences that distinguish one isoenzyme from another. |
|  | A) | True |
|  | B) | False |
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| 12 |  |  Skeletal and cardiac muscle have different forms of creatine phosphokinase. |
|  | A) | True |
|  | B) | False |
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| 13 |  |  The rate of an enzymatic reaction depends on the concentration of the substrate but not the concentration of the enzyme. |
|  | A) | True |
|  | B) | False |
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| 14 |  |  The higher the temperature, the faster the rate of an enzymatic reaction will be. |
|  | A) | True |
|  | B) | False |
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| 15 |  |  Human enzymes all have approximately the same temperature optimum, but highly varied pH optima. |
|  | A) | True |
|  | B) | False |
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| 16 |  |  Although these enzymes selectively remove phosphate groups, the phosphatase isolated from the prostate functions best at a lower pH than the phosphatase isolated from bone tissue. |
|  | A) | True |
|  | B) | False |
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| 17 |  |  Many enzymes cannot function when they are completely purified and isolated from their natural chemical surroundings. |
|  | A) | True |
|  | B) | False |
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| 18 |  |  Metal ions that aid the function of enzymes can be called either coenzymes or cofactors for those enzymes. |
|  | A) | True |
|  | B) | False |
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| 19 |  |  Coenzymes are organic molecules that sometimes bind to the active site of an enzyme along with its substrate in order for the enzyme to function at its optimal rate. |
|  | A) | True |
|  | B) | False |
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| 20 |  |  Carbonic anhydrase is an enzyme that can catalyze the breakdown of carbonic acid (H2CO3) into carbon dioxide (CO2) and water (H2O), but it cannot catalyze the reverse reaction. |
|  | A) | True |
|  | B) | False |
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| 21 |  |  If there is a reversible chemical reaction between two molecules A and B, and more B than A is present at a given moment, then the law of mass action predicts this reaction will go toward the left (that is, more B will be converted to A). |
|  | A) | True |
|  | B) | False |
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| 22 |  |  For most metabolic pathways a single enzyme catalyzes all the reactions. |
|  | A) | True |
|  | B) | False |
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| 23 |  |  The nine-step enzymatic conversion of glucose to pyruvic acid is a metabolic pathway. The one-step enzymatic conversion of CO2 and H2O to carbonic acid is not. |
|  | A) | True |
|  | B) | False |
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| 24 |  |  An intermediate in a metabolic pathway may serve as the substrate for two or more different enzymes that catalyze reactions leading in different directions. |
|  | A) | True |
|  | B) | False |
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| 25 |  |  Some metabolic end-products can deactivate or inhibit the very enzymes that are responsible for their production. |
|  | A) | True |
|  | B) | False |
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| 26 |  |  Allosteric inhibitors bind at a site other than the active site to decrease enzyme activity. |
|  | A) | True |
|  | B) | False |
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| 27 |  |  Suppose enzyme3 catalyzes the third step in a metabolic pathway where intermediate G is converted to intermediate H. An inborn error of metabolism resulting in a defective enzyme3 would result in a surplus of G and deficiency of H. |
|  | A) | True |
|  | B) | False |
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| 28 |  |  Albinism is the result of an inherited defect in an enzyme that produces skin pigment. |
|  | A) | True |
|  | B) | False |
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| 29 |  |  The fundamental point of cellular metabolism is to increase the amount of entropy in the system. |
|  | A) | True |
|  | B) | False |
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| 30 |  |  Entropy is a measure of the amount of free energy in a system. |
|  | A) | True |
|  | B) | False |
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| 31 |  |  Photosynthesis is an endergonic reaction. |
|  | A) | True |
|  | B) | False |
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| 32 |  |  The human body is unable to carry out any endergonic reactions because it does not have any photosynthetic pigments and cannot synthesize organic nutrients. |
|  | A) | True |
|  | B) | False |
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| 33 |  |  The complete oxidation of glucose to CO2 + H2O is an exergonic reaction. |
|  | A) | True |
|  | B) | False |
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| 34 |  |  The oxidation of 1 gram of glucose to CO2 + H2O will release more calories when done in small, enzymatically-controlled steps within a cell than when done in a single step by simply touching a match to a 1 gram of glucose. |
|  | A) | True |
|  | B) | False |
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| 35 |  |  One Calorie will raise the temperature of one liter of water one degree Celsius. |
|  | A) | True |
|  | B) | False |
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| 36 |  |  A cell must maintain a state of high entropy to stay alive. |
|  | A) | True |
|  | B) | False |
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| 37 |  |  Exergonic reactions in a cell are often directly coupled to endergonic reactions. |
|  | A) | True |
|  | B) | False |
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| 38 |  |  The endergonic reaction to which most exergonic reactions of a cell are linked is ATP → ADP + Pi + Energy. |
|  | A) | True |
|  | B) | False |
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| 39 |  |  When a molecule is reduced the molecule will gain one or more electrons. |
|  | A) | True |
|  | B) | False |
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| 40 |  |  Oxidation means a reaction in which some atom or molecule combines with oxygen. |
|  | A) | True |
|  | B) | False |
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| 41 |  |  In the course of performing its role, a reducing agent becomes oxidized. |
|  | A) | True |
|  | B) | False |
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| 42 |  |  It is impossible for an oxidation reaction to occur without a reduction reaction occurring simultaneously. |
|  | A) | True |
|  | B) | False |
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| 43 |  |  If a molecule picks up two hydrogen atoms, it becomes reduced. |
|  | A) | True |
|  | B) | False |
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| 44 |  |  It is possible for the same molecule to serve as both an oxidizing agent and a reducing agent, alternating between the oxidized and reduced forms. |
|  | A) | True |
|  | B) | False |
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| 45 |  |  The structure of the coenzyme NAD is very similar to the structure of the universal energy carrier ATP. |
|  | A) | True |
|  | B) | False |
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| 46 |  |  NADH is a reducing agent. |
|  | A) | True |
|  | B) | False |
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| 47 |  |  NAD is derived from niacin, a water-soluble vitamin known as B3. |
|  | A) | True |
|  | B) | False |
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| 48 |  |  FAD can accept two electrons and become FADH2, but NAD can only accept one electron and become NADH. |
|  | A) | True |
|  | B) | False |
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| 49 |  |  Since the vitamin riboflavin (vitamin B2) is converted to a coenzyme that transfers electrons in the energy-producing reactions, eating riboflavin supplements provides extra energy. |
|  | A) | True |
|  | B) | False |
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| 50 |  |  In a hypothetical reaction XH2 + Y → X + YH2, the compound X is a reducing agent. |
|  | A) | True |
|  | B) | False |
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| 51 |  |  In a hypothetical reaction XH2 + Y → X + YH2, the compound Y becomes oxidized. |
|  | A) | True |
|  | B) | False |
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