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| 1 |  |  The elasticity of skeletal muscle fibers is primarily due to the presence of this protein: (pp. 421-422; table 12.1) |
|  | A) | titin |
|  | B) | globular actin |
|  | C) | troponin |
|  | D) | collagen |
|  | E) | tropomyosin |
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| 2 |  |  T-tubules are extensions of the______________ in skeletal muscle (p. 421; table 12.1) |
|  | A) | sarcoplasmic reticulum |
|  | B) | plasma membrane |
|  | C) | junctional folds |
|  | D) | cytoskeleton |
|  | E) | thick filament |
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| 3 |  |  All of the following are structural components of the neuromuscular junction except: (p. 426; fig 12.7; table 12.2) |
|  | A) | active zones |
|  | B) | junctional folds |
|  | C) | basement membrane |
|  | D) | t-tubules |
|  | E) | acetylcholine receptors |
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| 4 |  |  After the power stroke has occurred during skeletal muscle contraction, what must occur in order for the acto-myosin cross-bridge to be released? (p. 431) |
|  | A) | ATP must be cleaved |
|  | B) | myosin must be de-phosphorylated |
|  | C) | ATP must bind with the myosin head |
|  | D) | Ca2+ must bind with myosin |
|  | E) | troponin must bind with tropomyosin |
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| 5 |  |  During excitation contraction coupling, Ca2+ binds troponin in both smooth and skeletal muscle. (pp. 429, 446) |
|  | A) | True |
|  | B) | False |
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| 6 |  |  Smooth muscle is capable of mitosis and hyperplasia. (p. 445) |
|  | A) | True |
|  | B) | False |
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| 7 |  |  If a person is completely bedridden, he/she can lose muscle strength at the rate of 3% per day. (p.448, table 12.6) |
|  | A) | True |
|  | B) | False |
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| 8 |  |  The ability of the muscle cell membrane to respond to stimuli with electric changes is known as |
|  | A) | excitability. |
|  | B) | conductivity. |
|  | C) | extensibility. |
|  | D) | elasticity. |
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| 9 |  |  The ability of the muscle cell to stretch under tension is known as |
|  | A) | excitability. |
|  | B) | conductivity. |
|  | C) | extensibility. |
|  | D) | elasticity. |
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| 10 |  |  The ability of the muscle cell to return to its initial length after being stretched is called |
|  | A) | excitability. |
|  | B) | conductivity. |
|  | C) | extensibility. |
|  | D) | elasticity. |
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| 11 |  |  Transverse tubules release calcium ions during muscle contraction. |
|  | A) | True |
|  | B) | False |
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| 12 |  |  Which of the following is a regulatory protein of muscle? |
|  | A) | actin |
|  | B) | myosin |
|  | C) | tropomyosin |
|  | D) | titin |
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| 13 |  |  Elastic filaments are composed of |
|  | A) | myosin. |
|  | B) | actin. |
|  | C) | titin. |
|  | D) | troponin. |
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| 14 |  |  The segment from one Z disc to the next is called a(n) |
|  | A) | A band. |
|  | B) | sarcomere. |
|  | C) | H band. |
|  | D) | I band. |
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| 15 |  |  When fine control of a muscle is required, the motor units are small. |
|  | A) | True |
|  | B) | False |
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| 16 |  |  Flaccid paralysis can be caused by |
|  | A) | pesticides. |
|  | B) | cholinesterase inhibitors. |
|  | C) | curare. |
|  | D) | acetylcholinesterase. |
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| 17 |  |  The resting membrane potential (RMP) for a skeletal muscle cell is |
|  | A) | -90mV. |
|  | B) | -30mV. |
|  | C) | 1.5mV. |
|  | D) | 12 V. |
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| 18 |  |  In a muscle contraction, the myofilaments shorten. |
|  | A) | True |
|  | B) | False |
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| 19 |  |  The time in which the muscle will not respond to a new stimulus is called the |
|  | A) | latent period. |
|  | B) | contraction phase. |
|  | C) | relaxation phase. |
|  | D) | refractory period. |
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| 20 |  |  For a muscle to lift a heavier weight, the individual muscle fibers contract more strongly. |
|  | A) | True |
|  | B) | False |
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| 21 |  |  If you attempt to lift a heavy object but it doesn't move, what type of contraction have you performed? |
|  | A) | concentric |
|  | B) | eccentric |
|  | C) | isotonic |
|  | D) | isometric |
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| 22 |  |  If you are drinking and put the glass down, this is a(an) __________ contraction. |
|  | A) | concentric |
|  | B) | eccentric |
|  | C) | isotonic |
|  | D) | isometric |
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| 23 |  |  A brief activity using maximum muscular effort is fueled best by the |
|  | A) | phosphagen system. |
|  | B) | aerobic system. |
|  | C) | glycogen-lactic acid system. |
|  | D) | citric acid system. |
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| 24 |  |  Which of the following statements about slow-twitch muscle fibers is false? |
|  | A) | Slow-twitch muscle fibers are smaller than fast-twitch fibers. |
|  | B) | Slow-twitch muscle fibers are anaerobic. |
|  | C) | Slow-twitch muscle fibers are fatigue resistant. |
|  | D) | Slow-twitch muscle fibers have abundant mitochondrion and myoglobin. |
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| 25 |  |  A stronger muscle contraction produced by a series of action potentials being sent to a motor unit is known as recruitment. |
|  | A) | True |
|  | B) | False |
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| 26 |  |  Acetylcholine and norepinephrine cause some smooth muscle cells to contract and yet inhibit cell contraction in others, depending on the type of membrane receptors present. |
|  | A) | True |
|  | B) | False |
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| 27 |  |  Smooth muscle is more sensitive to a difference in resting muscle length on peak contraction potential than skeletal muscle. |
|  | A) | True |
|  | B) | False |
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| 28 |  |  The thick myofilament consists of many molecules of this protein: |
|  | A) | myosin |
|  | B) | actin |
|  | C) | tropomyosin |
|  | D) | troponin |
|  | E) | ATPase |
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| 29 |  |  The sarcomeres are separated by: |
|  | A) | A bands |
|  | B) | I bands |
|  | C) | H bands |
|  | D) | Z discs |
|  | E) | A discs |
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| 30 |  |  One nerve fiber and all the muscle fibers it innervates are collectively called a: |
|  | A) | motor unit |
|  | B) | somatic motor group |
|  | C) | recruitment group |
|  | D) | fatigue unit |
|  | E) | synapse |
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| 31 |  |  This chemical carries the stimulating message across the neuromuscular junction: |
|  | A) | synapse |
|  | B) | myosin |
|  | C) | potassium |
|  | D) | gamma-aminobutyric acid |
|  | E) | acetylcholine |
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| 32 |  |  During excitation-contraction coupling, calcium ions bind to this skeletal muscle protein: |
|  | A) | acetylcholinesterase |
|  | B) | troponin |
|  | C) | actin |
|  | D) | myosin |
|  | E) | ATPase |
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| 33 |  |  The myosin heads bind to a monomer of this protein: |
|  | A) | tropomyosin |
|  | B) | troponin |
|  | C) | G-actin |
|  | D) | acetylcholinesterase |
|  | E) | ATPase |
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| 34 |  |  When the muscle action potential stops, calcium ions are pumped from the cytosol back into the: |
|  | A) | terminal cisternal |
|  | B) | transverse tubules |
|  | C) | thick filaments |
|  | D) | troponin |
|  | E) | mitochondria |
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| 35 |  |  _____ occurs when a muscle twitches more strongly as stimulation frequency is increased to 20/sec. |
|  | A) | graded response |
|  | B) | Treppe |
|  | C) | Threshold |
|  | D) | Tetany |
|  | E) | Isometric contraction |
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| 36 |  |  Fatigue can be caused by all of the following except: |
|  | A) | low acetylcholine supplies |
|  | B) | low pH in sarcoplasm |
|  | C) | excess of myoglobin |
|  | D) | excess of lactic acid |
|  | E) | reduced ATP concentrations |
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| 37 |  |  Fast-twitch fibers: |
|  | A) | have a lot of myoglobin |
|  | B) | mainly synthesize ATP by aerobic respiration |
|  | C) | have more mitochondria |
|  | D) | are white |
|  | E) | are very resistant to fatigue |
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| 38 |  |  Smooth muscles: |
|  | A) | have Z-discs |
|  | B) | lack T-tubules |
|  | C) | contain troponin |
|  | D) | are multinucleate |
|  | E) | are innervated by somatic nerve fibers |
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