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| 1 |  |  How does newly synthesized mRNA pass from the membrane-bound nucleus into the cytoplasm? (p.141, pictured in figs. 5.5 and 5.7) |
|  | A) | it passes through nuclear pores |
|  | B) | it is exocytosed from the nucleus |
|  | C) | it is actively transported by a special ATPase |
|  | D) | it passes across the membrane, facilitated by carrier proteins |
|  | E) | it is transported in clathrin-coated vesicles |
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| 2 |  |  Proteins which serve as "spools" to help organize chromatin are called: (p. 143) |
|  | A) | clathrin |
|  | B) | histones |
|  | C) | cytosines |
|  | D) | chaperones |
|  | E) | polymerases |
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| 3 |  |  Where would you find an anticodon? (p. 148) |
|  | A) | on mRNA |
|  | B) | on a ribosome |
|  | C) | on the tRNA |
|  | D) | on DNA |
|  | E) | on a protein |
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| 4 |  |  During what phase of the cell cycle is DNA replicated? (p. 155) |
|  | A) | anaphase |
|  | B) | G1 |
|  | C) | G2 |
|  | D) | S |
|  | E) | telophase |
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| 5 |  |  Proteins which will remain within the cytosol of the cell are usually synthesized on the rough endoplasmic reticulum. (p. 151) |
|  | A) | True |
|  | B) | False |
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| 6 |  |  A mature germ cell (egg or sperm) is haploid. (pp. 160-161) |
|  | A) | True |
|  | B) | False |
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| 7 |  |  An example of genetic co-dominance is shown in a person who has blood type AB. (p. 162) |
|  | A) | True |
|  | B) | False |
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| 8 |  |  Chromatin consists of DNA only. |
|  | A) | True |
|  | B) | False |
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| 9 |  |  A DNA molecule wraps around a cluster of histones and appears as granules on the chromatin thread. This granule is called a |
|  | A) | nucleosome. |
|  | B) | nucleotide. |
|  | C) | base pair. |
|  | D) | none of the above |
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| 10 |  |  In the movie GATTACA, what do the letters in the title represent? |
|  | A) | guanine, cytosine, adenine, and thymine |
|  | B) | nitrogenous bases |
|  | C) | a piece of the genetic sequence of DNA |
|  | D) | all of the above |
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| 11 |  |  For the sequence GATTACA, what would the complementary DNA strand be? |
|  | A) | CUAAUGU |
|  | B) | GATTACA |
|  | C) | CTAATGT |
|  | D) | TCGGCTC |
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| 12 |  |  Which of the following is not contained in a nucleotide? |
|  | A) | sugar |
|  | B) | phosphate group |
|  | C) | glycerol |
|  | D) | nitrogenous bases |
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| 13 |  |  Which of the following is a copy of the genetic code that directs the synthesis of a particular protein? |
|  | A) | DNA |
|  | B) | mRNA |
|  | C) | tRNA |
|  | D) | rRNA |
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| 14 |  |  Which of the following, found in the nucleus, contains the genetic code for the synthesis of many different proteins? |
|  | A) | DNA |
|  | B) | mRNA |
|  | C) | tRNA |
|  | D) | rRNA |
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| 15 |  |  Which of the following delivers amino acids to the ribosome? |
|  | A) | DNA |
|  | B) | mRNA |
|  | C) | tRNA |
|  | D) | rRNA |
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| 16 |  |  Genetic translation is the process of copying information from the DNA to the RNA. |
|  | A) | True |
|  | B) | False |
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| 17 |  |  A molecule that has an anticodon on one end and a specific amino acid on the other is called |
|  | A) | mRNA. |
|  | B) | rRNA. |
|  | C) | tRNA. |
|  | D) | chaperone. |
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| 18 |  |  A cell that is active in protein synthesis has many ribosomes. |
|  | A) | True |
|  | B) | False |
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| 19 |  |  What reads the codons on mRNA and binds to appropriate tRNA? |
|  | A) | small ribosomal subunit |
|  | B) | large ribosomal subunit |
|  | C) | Golgi complex |
|  | D) | SER |
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| 20 |  |  Which of the following has an enzyme that forms peptide bonds between amino acids? |
|  | A) | small ribosomal subunit |
|  | B) | large ribosomal subunit |
|  | C) | Golgi complex |
|  | D) | SER |
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| 21 |  |  All mutations to DNA cause change in the function of the protein synthesized from that DNA. |
|  | A) | True |
|  | B) | False |
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| 22 |  |  DNA replication occurs in which phase of the cell cycle? |
|  | A) | G1 phase |
|  | B) | S phase |
|  | C) | G2 phase |
|  | D) | M phase |
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| 23 |  |  The G1, S, and G2 phases together are called |
|  | A) | prophase. |
|  | B) | metaphase. |
|  | C) | interphase. |
|  | D) | telophase. |
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| 24 |  |  Chromosomes appear and the nuclear envelope disintegrates during which phase of mitosis? |
|  | A) | anaphase |
|  | B) | metaphase |
|  | C) | prophase |
|  | D) | telophase |
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| 25 |  |  Chromatids migrate toward opposite poles of the cell during which phase? |
|  | A) | anaphase |
|  | B) | metaphase |
|  | C) | prophase |
|  | D) | telophase |
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| 26 |  |  Chromosomes line up in the middle of the cell and the mitotic spindle forms during |
|  | A) | anaphase. |
|  | B) | metaphase. |
|  | C) | prophase. |
|  | D) | telophase. |
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| 27 |  |  Excessive growth factors or growth factor receptors implicated in the development of cancer are caused by |
|  | A) | oncogenes. |
|  | B) | tumor-suppressing factors. |
|  | C) | peroxisomes. |
|  | D) | macrophages. |
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| 28 |  |  If both alleles of a gene are the same, the person is heterozygous for that trait. |
|  | A) | True |
|  | B) | False |
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| 29 |  |  If a mother has blood type O (ii) and the father has type AB (IAIB) their children can only be either type A or B. |
|  | A) | True |
|  | B) | False |
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| 30 |  |  When a red flower crossed with a white flower produces a pink flower, which of the following is demonstrated? |
|  | A) | codominance |
|  | B) | polygenic inheritance |
|  | C) | pleiotrophy |
|  | D) | incomplete dominance |
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| 31 |  |  If the mother is a carrier for hemophilia (X-linked trait) but the father does not have this condition, what is the chance that their son will have the disease? |
|  | A) | 75% |
|  | B) | 50% |
|  | C) | 25% |
|  | D) | 0% |
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| 32 |  |  For this same couple, what is the chance that their daughter will have the disease? |
|  | A) | 75% |
|  | B) | 50% |
|  | C) | 25% |
|  | D) | 0% |
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| 33 |  |  Which of the following nitrogenous bases is not in RNA? |
|  | A) | uracil |
|  | B) | guanine |
|  | C) | adenine |
|  | D) | cytosine |
|  | E) | thymine |
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| 34 |  |  If one strand of a DNA molecule has this sequence--CTTTAT--what will the RNA codons be when transcribed? |
|  | A) | GAAATA |
|  | B) | GAAAUA |
|  | C) | CAAAUA |
|  | D) | CTTTAT |
|  | E) | CATAUU |
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| 35 |  |  Messenger RNA is synthesized in the: |
|  | A) | nucleolus |
|  | B) | spliceosome |
|  | C) | ribosome |
|  | D) | polysome |
|  | E) | nucleus |
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| 36 |  |  Translation occurs in the: |
|  | A) | peroxisomes |
|  | B) | nucleolus |
|  | C) | spliceosomes |
|  | D) | ribosomes |
|  | E) | nucleus |
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| 37 |  |  This molecule brings the correct amino acid to the place of translation: |
|  | A) | DNA |
|  | B) | intron |
|  | C) | t-RNA |
|  | D) | m-RNA |
|  | E) | r-RNA |
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| 38 |  |  After protein production, it may move into this structure just before exocytosis: |
|  | A) | ribosome |
|  | B) | nucleus |
|  | C) | Golgi complex |
|  | D) | clathrin |
|  | E) | cytoplasmic inclusion |
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| 39 |  |  If a man who has X-linked hemophilia marries a woman carrying but not having the same condition, what is the chance of their having a hemophilic son? |
|  | A) | 100% |
|  | B) | 25% |
|  | C) | 75% |
|  | D) | 33% |
|  | E) | 50% |
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| 40 |  |  The stage in cell life where it performs most of its assigned functions is: |
|  | A) | G1 |
|  | B) | S |
|  | C) | G2 |
|  | D) | prophase |
|  | E) | metaphase |
|  | F) | 1 |
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| 41 |  |  This is not a characteristic of cancer cells: |
|  | A) | contact inhibition |
|  | B) | metastatic |
|  | C) | malignant |
|  | D) | anaplastic |
|  | E) | displace normal cells |
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