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| 1 |  |  Traits showing non-Mendelian extranuclear inheritance are always inherited from the mother. |
|  | A) | True. |
|  | B) | False. |
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| 2 |  |  The molecules used to carry out photosynthesis are encoded in nuclear DNA and mitochondrial DNA. |
|  | A) | True. |
|  | B) | False. |
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| 3 |  |  A chloroplast URF is a cpDNA coding sequence with a product of unknown function. |
|  | A) | True. |
|  | B) | False. |
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| 4 |  |  Molecular evidence suggests that DNA sequences may have been transferred between mtDNA and nuclear DNA. |
|  | A) | True. |
|  | B) | False. |
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| 5 |  |  Variegated four o'clock leaves have white patches among the green areas due to a mtDNA mutation that blocks electron transport. |
|  | A) | True. |
|  | B) | False. |
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| 6 |  |  Mitochondrial inheritance shows Mendel's principle of independent assortment. |
|  | A) | True. |
|  | B) | False. |
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| 7 |  |  Mitochondrial genomes are relatively uniform in size. |
|  | A) | True. |
|  | B) | False. |
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| 8 |  |  The codon UGA specifies 'stop' in all compartments of a human cell. |
|  | A) | True. |
|  | B) | False. |
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| 9 |  |  The gene gun is a tool for incorporating foreign DNA into organelles. |
|  | A) | True. |
|  | B) | False. |
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| 10 |  |  The Trypanosoma kinetoplast is the site of RNA editing. |
|  | A) | True. |
|  | B) | False. |
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| 11 |  |  __________ is organized into nucleosomes.
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|  | A) | mtDNA |
|  | B) | kDNA |
|  | C) | nDNA |
|  | D) | cpDNA |
|  | E) | tRNA |
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| 12 |  |  __________ encoded by organelles may recognize codons differently.
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|  | A) | mtDNA |
|  | B) | kDNA |
|  | C) | nDNA |
|  | D) | cpDNA |
|  | E) | tRNA |
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| 13 |  |  __________ is composed of maxicircles and minicircles.
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|  | A) | mtDNA |
|  | B) | kDNA |
|  | C) | nDNA |
|  | D) | cpDNA |
|  | E) | tRNA |
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| 14 |  |  __________ is probably derived from a relative of purple non-sulfur bacteria.
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|  | A) | mtDNA |
|  | B) | kDNA |
|  | C) | nDNA |
|  | D) | cpDNA |
|  | E) | tRNA |
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| 15 |  |  ___________ is probably derived from an ancestral cyanobacterium.
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|  | A) | mtDNA |
|  | B) | kDNA |
|  | C) | nDNA |
|  | D) | cpDNA |
|  | E) | tRNA |
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| 16 |  |  Organellar genomes derived from only one gamete show a _________ pattern of inheritance.
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|  | A) | homoplasmic |
|  | B) | heteroplasmic |
|  | C) | uniparental |
|  | D) | biparental |
|  | E) | isogamous |
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| 17 |  |  A cell with nonidentical mitochondrial genomes is said to be:
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|  | A) | homoplasmic |
|  | B) | heteroplasmic |
|  | C) | uniparental |
|  | D) | biparental |
|  | E) | isogamous |
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| 18 |  |  Organellar genomes derived from both gametes show a _________ pattern of inheritance.
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|  | A) | homoplasmic |
|  | B) | heteroplasmic |
|  | C) | uniparental |
|  | D) | biparental |
|  | E) | isogamous |
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| 19 |  |  A cell with chloroplast genomes which are identical is said to be:
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|  | A) | homoplasmic |
|  | B) | heteroplasmic |
|  | C) | uniparental |
|  | D) | biparental |
|  | E) | isogamous |
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| 20 |  |  An organism that produces mating cells of the same size is said to be:
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|  | A) | homoplasmic |
|  | B) | heteroplasmic |
|  | C) | uniparental |
|  | D) | biparental |
|  | E) | isogamous |
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| 21 |  |  With traits showing biparental inheritance, such as leaf variegation in geraniums, reciprocal crosses usually:
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|  | A) | yield the same results. |
|  | B) | yield different results. |
|  | C) | yield result which can seldom be predicted |
|  | D) | yield exactly opposite results |
|  | E) | none of the above |
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| 22 |  |  In the study of eukaryotes, DNA-specific dyes and light microscopy reveal DNA molecules:
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|  | A) | in the cell wall |
|  | B) | in the matrix of the mitochondrion |
|  | C) | in the cytoplasm |
|  | D) | in ribosomes |
|  | E) | in all of these sites |
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| 23 |  |  Which process(es) take place in the mitochondrion?
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|  | A) | Krebs cycle |
|  | B) | Calvin cycle |
|  | C) | photosynthesis |
|  | D) | a & b |
|  | E) | b & c |
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| 24 |  |  Mitochondria resemble bacteria in terms of:
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|  | A) | ribosomal genes |
|  | B) | size |
|  | C) | replication |
|  | D) | circular chromosome |
|  | E) | all of the above |
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| 25 |  |  Inhibitors of bacterial translation generally:
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|  | A) | inhibit eukaryotic cytoplasmic protein synthesis |
|  | B) | inhibit mitochondrial protein synthesis |
|  | C) | inhibit chloroplast protein synthesis |
|  | D) | have no effect on eukaryotic cells |
|  | E) | b and c |
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| 26 |  |  Which of the following is true of organelles?
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|  | A) | DNA organized into nucleosomes by histones |
|  | B) | translation is not inhibited by bacterial antibiotics |
|  | C) | N-formyl methionine and tRNAfmet used in translation. |
|  | D) | all of the above |
|  | E) | none of the above |
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| 27 |  |  Which sequences would be most similar?
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|  | A) | mtDNA in mitochondrial Eve and modern human mtDNA |
|  | B) | Neanderthal mtDNA and Cro-Magnon mtDNA |
|  | C) | mtDNA from the 5,000-year-old 'ice man' and modern human mtDNA |
|  | D) | Chimpanzee mtDNA and modern human mtDNA |
|  | E) | modern human mtDNA and bacterial DNA |
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| 28 |  |  Which are the least related in terms of human mtDNA sequence?
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|  | A) | father and daughter |
|  | B) | mother and son |
|  | C) | nephew and maternal aunt |
|  | D) | niece and maternal uncle |
|  | E) | grandchild and maternal grandmother |
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| 29 |  |  A cross is conducted between isogamous algae that show uniparental inheritance where mtDNA is inherited from one parent and cpDNA is inherited from the other. A mutation in cpDNA causes a yellow color, and a mutation in mtDNA confers chloramphenicol resistanc From the following mating:
| yellow/chloramphenicol resistant | x | green/chloramphenicol sensitive |
Which of the following ratios might be observed in the resulting haploid progeny?
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|  | A) | 2 yellow/resistant, 2 yellow/sensitive |
|  | B) | 2 green/resistant, 2 green/sensitive |
|  | C) | 4 green/sensitive |
|  | D) | 4 green/resistant |
|  | E) | 1 yellow/resistant, 1 yellow/sensitive, 1 green/resistant, 1 green/sensitive |
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| 30 |  |  A cross is performed between cells of two genetically different yeast strains, and a long period of vegetative growth of the resultant diploid cells ensues. What is true of the marker genes?
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|  | A) | mitochondrial markers segregate, nuclear markers do not |
|  | B) | nuclear markers segregate, mitochondrial markers do not |
|  | C) | both mitochondrial and nuclear markers segregate |
|  | D) | mitochondrial and nuclear markers from only one parent are observed |
|  | E) | neither nuclear nor mitochondrial markers segregate |
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| 31 |  |  Variable expression of the MERRF syndrome arises from:
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|  | A) | recombination between nuclear and mtDNA |
|  | B) | homoplasmic cells |
|  | C) | mitotic segregation |
|  | D) | nuclear genes |
|  | E) | environmental factors |
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| 32 |  |  What mode of inheritance is suggested by the following pedigree?
 (6.0K)
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|  | A) | biparental |
|  | B) | uniparental; maternal |
|  | C) | uniparental; paternal |
|  | D) | X-linked recessive |
|  | E) | Y-linked |
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| 33 |  |  A form of male sterility in corn exhibits non-Mendelian inheritance. Plants of a male-sterile line crossed with pollen from a wild-type (not sterile) line give all male-sterile plants. Some lines of corn carry a dominant allele of a different, nuclear gene. This "restorer" (or Rf) allele restores pollen fertility in male-sterile lines. If a male-sterile plant is crossed with pollen from a plant homozygous for Rf, what will be the genotype and phenotype of the F1? Cytoplasmic genotype is indicated by [ ], male-sterile cytoplasm is indicated by "ms", and normal cytoplasm is indicated by "n".
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|  | A) | rf/rf [ms]; male-sterile |
|  | B) | Rf/Rf [ms]; fertile |
|  | C) | Rf/rf [n]; fertile |
|  | D) | Rf/rf [ms]; fertile |
|  | E) | Rf/rf [ms]; male-sterile |
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