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| 1 |  |  In humans ____ pairs of chromosomes are known as autosomes and ____ pair of chromosomes are known as sex chromosomes. |
|  | A) | 23, 46 |
|  | B) | 21, 2 |
|  | C) | 22, 1 |
|  | D) | 45, 1 |
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| 2 |  |  Duplicated strands of DNA are called ________ and are connected to each other by the __________. |
|  | A) | chromatids; centrosomes |
|  | B) | chromatin; mitochondria |
|  | C) | chromatids; centromere |
|  | D) | centromeres; chromosomes |
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| 3 |  |  The type of cell division that results in the formation of gametes or sex cells is __________. |
|  | A) | mitosis |
|  | B) | meiosis |
|  | C) | nondisjunction |
|  | D) | somatic division |
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| 4 |  |  The diploid (2n) cells of the testes that begin the meiotic process are called: |
|  | A) | spermatids |
|  | B) | secondary spermatocytes |
|  | C) | sperm |
|  | D) | primary spermatocytes |
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| 5 |  |  A male with two or more X chromosomes along with a single Y has ________ syndrome. |
|  | A) | Turner |
|  | B) | Klinefelter |
|  | C) | Down |
|  | D) | Jacobs |
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| 6 |  |  A/an ________________ provides a visual display of the chromosomes arranged by size, shape, and banding patterns. |
|  | A) | chorionic villus sampling |
|  | B) | karyotype |
|  | C) | syndrome |
|  | D) | amniocentesis |
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| 7 |  |  Cells that are examined in karyotyping of a fetus usually come from: |
|  | A) | chorionic villi |
|  | B) | skin cells |
|  | C) | amniotic fluid |
|  | D) | Both 1 and 3 are correct. |
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| 8 |  |  The process of programmed cell death is called |
|  | A) | mitosis. |
|  | B) | cytokinesis. |
|  | C) | apoptosis. |
|  | D) | karyokinesis. |
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| 9 |  |  During the cell cycle, interphase |
|  | A) | is a time of RNA synthesis. |
|  | B) | is truly a resting stage. |
|  | C) | has a minimum of cellular activity before DNA replication. |
|  | D) | is a time of DNA replication and cellular activity before DNA replication. |
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| 10 |  |  During which part of interphase does DNA replicate? |
|  | A) | G1 phase |
|  | B) | S phase |
|  | C) | G2 phase |
|  | D) | telophase |
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| 11 |  |  During __________ the cytoplasm is divided. |
|  | A) | karyokinesis |
|  | B) | amniocentesis |
|  | C) | cytokinesis |
|  | D) | replecation |
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| 12 |  |  The structures that begin to attach to centromeres as the chromosomes continue to shorten and thicken during prophase are: |
|  | A) | asters |
|  | B) | chromatin |
|  | C) | telomeres |
|  | D) | spindle fibers |
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| 13 |  |  Which of the following is the correct order of the phases of mitosis? |
|  | A) | prophase, anaphase, telophase, metaphase |
|  | B) | metaphase, telophase, prophase, anaphase |
|  | C) | prophase, metaphase, anaphase, telophase |
|  | D) | telophase, prophase, anaphase, metaphase |
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| 14 |  |  During what stage of mitosis do the chromosomes condense and become visible? |
|  | A) | prophase |
|  | B) | metaphase |
|  | C) | anaphase |
|  | D) | telophase |
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| 15 |  |  What stage of mitosis is characterized by a fully formed spindle and the alignment of chromosomes at the equator of the cell? |
|  | A) | prophase |
|  | B) | metaphase |
|  | C) | anaphase |
|  | D) | telophase |
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| 16 |  |  _____ between non-sister chromatids during synapsis will give a recombinant DNA having chromosomes with different genes. |
|  | A) | Synapsis |
|  | B) | Replication |
|  | C) | Interkinesis |
|  | D) | Crossing-over |
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| 17 |  |  In metaphase I of meiosis I, the chromosomes |
|  | A) | separate from their homologue. |
|  | B) | line up singly at the equator. |
|  | C) | appear random and singly. |
|  | D) | line up with their homologue at the equator. |
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| 18 |  |  Oogenesis differs from spermatogenesis in that oogenesis results in ______. |
|  | A) | four diploid cells |
|  | B) | four haploid eggs cells |
|  | C) | two diploid cells, two haploid cells |
|  | D) | one haploid egg cell, three polar bodies |
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| 19 |  |  Which of the following is NOT a characteristic of Down syndrome? |
|  | A) | wide, round face |
|  | B) | under-developed gonads |
|  | C) | fold on upper eyelid |
|  | D) | mental retardation |
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| 20 |  |  The loss of an end from chromosome 7 results in |
|  | A) | Turner syndrome. |
|  | B) | Alagille syndrome. |
|  | C) | Williams syndrome. |
|  | D) | Cri du Chat. |
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