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1
____________ refers to the physical make-up of an organism.
A)Allele
B)Genome
C)Genotype
D)Phenotype
2
A ___________ is used to illustrate the possible genotype and phenotype of an offspring.
A)Chromosome map
B)Mendelian square
C)Punnett square
D)Chi square
3
_______ is an autosomal recessive genetic disorder that involves faulty chloride channels and is more commonly occurs in Caucasians.
A)Phenylketonuria
B)Adrenoleukodystrophy
C)Cystic fibrosis
D)Tay Sachs disease
4
______ occurs when alleles are equally expressed in the heterozygote.
A)Co-dominance
B)Penetrance
C)Incomplete dominance
D)Continuous variation
5
_______ is called the bleeder's disease because the affected person's blood does not clot or clots very slowly.
A)Hemophilia
B)Huntington disease
C)Sickle-cell disease
D)None of the above.
6
The possible or alternate forms of a gene having the same position on a pair of chromosomes and affecting the same trait are called______.
A)chromatids
B)alleles
C)telomeres
D)centrioles
7
Choose the following letter designation for attached/unattached earlobes that represents the heterozygous genotype.
A)EE
B)Ee
C)ee
D)None of the choices are correct.
8
Which of the following letter combinations represents the homozygous condition?
A)RR
B)rr
C)Rr
D)Both RR and rr.
9
If two parents are heterozygous for a particular trait, which of the following ratios would best reflect the phenotype of their offspring?
A)3:1
B)2:1
C)1:1
D)None of the choices are correct.
10
Individuals who appear to be phenotypically normal but can pass on an allele for a particular genetic disorder are called ______.
A)dominant
B)carriers
C)latent
D)karyotypes
11
The rough coat of a guinea pig is dominant gene to the smooth coat. If 100% of the offspring are smooth coated, what are the genotypes and phenotypes of the parent guinea pigs?
A)RR - homozygous dominant rough and Rr - heterozygous rough
B)Rr - heterozygous rough and rr homozygous recessive smooth
C)Both parents are rr - homozygous recessive smooth
D)RR - homonzygous dominant rough and rr - homozygous recessive smooth.
12
In humans, the gene for Huntington disease is dominant to the normal gene. If a man that is homozygous recessive and a woman that is heterozygous decide to have children, what are the chances of having a child with Huntington disease?
A)0%
B)25%
C)50%
D)100%
13
___________ is an autosomal recessive disorder that is more common in people of Jewish descent. It involves a lysosomal dysfunction where they lack the enzyme Hex A.
A)Cystic fibrosis
B)Tay-Sachs disease
C)Alagille syndrome
D)Neurofibromatosis
14
An autosomal recessive disorder that affects nervous system development due to the lack of the enzyme needed for normal metabolism of phenylalanine is
A)cystic fibrosis.
B)Tay-Sachs disease.
C)sickle-cell disease.
D)PKU (phenylketonuria).
15
Which of the following is not considered multifactorial?
A)diabetes
B)hypertension
C)cystic fibrosis
D)some cancers
16
Traits that involve more than one set of alleles are called _____.
A)codominant
B)incomplete
C)heterozygous
D)polygenic
17
The following blood types are possible if parents have genotypes AO and BO.
A)A
B)B
C)O
D)All of these are correct.
18
____________ is considered to be the most common cause of inherited mental impairment and is more common in males.
A)Down syndrome
B)B. Hurler syndrome
C)Achoo syndrome
D)Fragile X syndrome
19
Which of the following is expected to be more common in male offspring than female?
A)Hemophilia
B)Sickle-cell disease
C)Huntington disease
D)Marfan syndrome
20
Duchenne muscular dystrophy is an X-linked recessive disorder caused by the lack of dystrophin which causes ____ to leak into muscles cells which then dissolve to be replaced by fibrous connective tissue.
A)huntingtin
B)chloride ions
C)oxygen
D)calcium





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