Activation of many eukaryotic genes require chromatin remodeling. Several different proteins carry out remodeling, and all of them have ATPase activity that harvest energy from ATP hydrolysis to use for remodeling. One of the two best studied complexes is SWI/SNF.

View the animation below, then complete the quiz to test your knowledge of the concept.

1	The basic subunit of chromatin is...
	A)	DNA
	B)	nucleosome
	C)	histone proteins
	D)	HO gene
	E)	histone acetyltransferase
2	Which of the following can physically block interactions between promoter DNA sequences and the proteins needed to initiate transcription?
	A)	RNA
	B)	nucleosome
	C)	histone proteins
	D)	HO gene
	E)	histone acetyltransferase
3	During chromatin remodeling, which of the following is acetylated to loosen its contact with the DNA?
	A)	DNA
	B)	nucleosome
	C)	histone proteins
	D)	HO gene
	E)	histone acetyltransferase
4	Chromatin rearrangement modifies the histone - DNA structure so that translation can occur.
	A)	True
	B)	False
5	The activities of Swi/Snf and the histone acetyltransferase modify the chromatin structure of the HO promoter region into a more open conformation.
	A)	True
	B)	False