View the animation below, then complete the quiz to test your knowledge of the concept.
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| 1 | According to the Holliday model, the first step of recombination involves a nick in |
 | A) | only one DNA strand of each of the two homologous chromosomes. |
| B) | only one DNA strand of only one of the two homologous chromosomes. |
| C) | both DNA strands of each of the two homologous chromosomes. |
| D) | both DNA strands of only one of the two homologous chromosomes. |
| E) | either one or both strands of each of the two homologous chromosomes. |
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| 2 | Arrange the following in the proper order in which they occur during recombination.
1. Holliday junction formation
2. Strand invasion
3. Branch migration |
| A) | 1, 2, 3 |
| B) | 2, 1, 3 |
| C) | 2, 3, 1 |
| D) | 3, 2, 1 |
| E) | 3, 1, 2 |
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| 3 | After isomerization, cleavage by an endonuclease results in |
| A) | two nonrecombinant chromosomes, each containing a heteroduplex region. |
| B) | two nonrecombinant chromosomes, without heteroduplex regions. |
| C) | two recombinant chromosomes, each containing a heteroduplex region. |
| D) | two recombinant chromosomes, without heteroduplex regions. |
| E) | two chromosomes that are unchanged from the original chromosome. |
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| 4 | The Holliday junction consists of a single DNA strand containing genetic material from two different chromosomes. |
| A) | True |
| B) | False |
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| 5 | The Holliday model can be used to explain crossing over in meiosis. |
| A) | True |
| B) | False |