Objective: Identify the phenotypic expression of ALS disease and associate the genetic and cellular basis for its destructive action.

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1	Symptoms experiences in ALS patients include all of the following except:
	A)	loss of energy
	B)	inability to move muscles
	C)	loss of cognitive function
	D)	progressive to the point of being fatal
2	The consequence of ALS is:
	A)	slight tremors in the hands
	B)	blockages of major arteries preventing blood flow
	C)	death of specialized nerve cells in the spine that eventually result in body wide paralysis
	D)	deterioration of brain function
3	In relation to cell activity what is the basis of ALS?
	A)	Preventing mitochondria activity, disrupting their ability to produce the energy needed for cell survival.
	B)	Destruction of ribosomes so that proteins can’t be produced.
	C)	Over secretion by lysosomes causing intracellular digestion.
	D)	Inability for cells to remove waste products.
4	What is the genetic cause associated with ALS disease?
	A)	Gene coding for over secretion of the neurotransmitter called acetylcholine.
	B)	A mistake in the DNA that prevents muscle cells from taking up calcium.
	C)	A mutation that causes a faulty protein to be made that adheres to mitochondria.
	D)	A deletion error that prevents muscle fiber from being made properly.
5	What is the current limitation in the research findings to date regarding ALS?
	A)	Funding is insufficient to continue this aspect of the research.
	B)	There are very few people who are faced with the disease to study.
	C)	The study has not had enough time to draw any correlations between gene mutation and ALS.
	D)	The mutation that has been studied accounts only about two percent of the instances of ALS.