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I. Population Genetics A. Definitions of Populations B. Genotype and Allele Frequencies C. Hardy-Weinberg Equilibrium II. Evolutionary Forces A. Mutation B. Natural Selection 1. Selection against recessive homozygotes 2. Selection for recessive homozygotes 3. Selection for the heterozygote 4. Selection and complex traits C. Genetic Drift D. Gene Flow E. Interaction of the Evolutionary Forces F. Nonrandom Mating IV. Summary V. Supplemental Readings Special Topic: Tay-Sachs Disease: Genetic Drift or Natural Selection? |