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1 |  |  __________ pairs of cranial nerves originate from the brain, and __________ pairs of spinal nerves originate from the spinal cord. |
|  | A) | 2, 12 |
|  | B) | 8, 24 |
|  | C) | 12,31 |
|  | D) | 15,36 |
|  | E) | 16,38 |
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2 |  |  The part of the efferent division of the nervous system that transmits impulses from the CNS to smooth muscle, cardiac muscle, and glands is the |
|  | A) | somatic motor nervous system |
|  | B) | somatic sensory division |
|  | C) | visceral sensory division |
|  | D) | autonomic nervous system |
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3 |  |  Collections of neuron cell bodies outside the CNS are called |
|  | A) | ganglia. |
|  | B) | nerves. |
|  | C) | nerve tracts. |
|  | D) | nuclei. |
|  | E) | glands. |
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4 |  |  The major site for processing information and integrating mental processes is the |
|  | A) | ANS (parasympathetic division). |
|  | B) | ANS (sympathetic division). |
|  | C) | CNS. |
|  | D) | PNS. |
|  | E) | somatic motor nervous system. |
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5 |  |  In a neuron, the nucleus and chromatophilic substance are located in the |
|  | A) | axon. |
|  | B) | dendrites. |
|  | C) | neuron cell body. |
|  | D) | terminal boutons. |
|  | E) | collateral axon. |
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6 |  |  Axons end by branching to form small extensions with enlarged ends. The enlarged ends are called |
|  | A) | dendrites. |
|  | B) | neuron cell bodies. |
|  | C) | presynaptic terminals. |
|  | D) | postsynaptic membranes. |
|  | E) | axon hillocks. |
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7 |  |  Neuroglia cells with cytoplasmic extensions that form sheaths around axons in the CNS are called |
|  | A) | astrocytes. |
|  | B) | ependymal cells. |
|  | C) | microglia. |
|  | D) | oligodendrocytes. |
|  | E) | Schwann cells. |
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8 |  |  Which of these cell types produce and help circulate cerebrospinal fluid? |
|  | A) | astrocytes |
|  | B) | microglia |
|  | C) | ependymal cells |
|  | D) | Schwann cells |
|  | E) | oligodendrocytes |
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9 |  |  Which of these ions have ligand-gated channels in the plasma membrane of nerve and muscle cells? |
|  | A) | Cl- ions |
|  | B) | K+ ions |
|  | C) | Na+ ions |
|  | D) | Ca2+ ions |
|  | E) | all of these |
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10 |  |  In a resting cell, the resting membrane potential is between -70mV and -90mV. This occurs because |
|  | A) | there are extra Na+ ions outside the plasma membrane, and extra Cl- ions inside the plasma membrane. |
|  | B) | Na+ ions move with the concentration gradient to the outside of the cell. |
|  | C) | some K+ ions diffuse to immediately outside the plasma membrane. |
|  | D) | large protein ions diffuse to immediately outside the plasma membrane. |
|  | E) | fewer Ca2+ ions inside the plasma membrane make the inside more negative. |
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11 |  |  The sodium-potassium exchange pump transports __________ Na+ ions and __________ K+ ions for every ATP molecule used. |
|  | A) | 1,2 |
|  | B) | 2,2 |
|  | C) | 2,3 |
|  | D) | 3,2 |
|  | E) | 3,3 |
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12 |  |  If there is an increase in extracellular K+ ion concentration, the result is |
|  | A) | depolarization of the plasma membrane. |
|  | B) | hyperpolarization of the plasma membrane. |
|  | C) | little, if any, change in the resting membrane potential of the plasma membrane. |
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13 |  |  If the permeability of the plasma membrane to K+ ions increases, the result is |
|  | A) | depolarization of the plasma membrane. |
|  | B) | hyperpolarization of the plasma membrane. |
|  | C) | little, if any, change in the resting membrane potential of the plasma membrane. |
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14 |  |  If there is an increase in the extracellular Na+ ion concentration, the result is |
|  | A) | depolarization of the plasma membrane. |
|  | B) | hyperpolarization of the plasma membrane. |
|  | C) | little, if any, change in the resting membrane potential of the plasma membrane. |
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15 |  |  Voltage-gated Na+ ion channels are sensitive to changes in the extracellular concentration of |
|  | A) | Ca2+ ions. |
|  | B) | Cl- ions. |
|  | C) | K+ ions. |
|  | D) | proteins. |
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16 |  |  Small depolarizations of the plasma membrane, regardless of the cause of the depolarization, cause |
|  | A) | voltage-gated K+ ion channels to close. |
|  | B) | voltage-gated Na+ ion channels to open. |
|  | C) | voltage-gated Ca2+ ion channels to open. |
|  | D) | voltage-gated Cl- ion channels to open. |
|  | E) | both a and b |
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17 |  |  Which of these processes can cause a local potential? |
|  | A) | changes in membrane permeability |
|  | B) | ligands binding to their receptors |
|  | C) | mechanical stimulation |
|  | D) | changes in the charge across the plasma membrane |
|  | E) | all of these |
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18 |  |  Action potentials occur when the local potential |
|  | A) | becomes more negative. |
|  | B) | reaches zero. |
|  | C) | reaches the threshold. |
|  | D) | remains constant for a considerable period of time. |
|  | E) | causes a hyperpolarization. |
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19 |  |  When the plasma membrane is at rest, activation gates of the voltage-gated Na+ ion channels are __________ and inactivation gates are __________ . |
|  | A) | closed, closed |
|  | B) | closed, open |
|  | C) | open, closed |
|  | D) | open, open |
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20 |  |  The depolarization phase of the action potential begins when |
|  | A) | Na+ ions move into the cell. |
|  | B) | K+ ions move into the cell. |
|  | C) | Na+ ions move out of the cell. |
|  | D) | K+ ions move out of the cell. |
|  | E) | both a and b |
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21 |  |  The repolarization phase of the action potential occurs because |
|  | A) | voltage-gated Na+ ion channels open. |
|  | B) | voltage-gated K+ ion channels open. |
|  | C) | voltage-gated Na+ ion channels close. |
|  | D) | voltage-gated K+ ion channels close. |
|  | E) | both b and c |
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22 |  |  For the resting membrane potential to be reestablished after a series of action potentials, |
|  | A) | activation gates of voltage-gated Na+ ion channels are closed. |
|  | B) | inactivation gates of voltage-gated Na+ ion channels are open. |
|  | C) | voltage-gated K+ ion channels are closed. |
|  | D) | the sodium-potassium exchange pump is functioning. |
|  | E) | all of these |
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23 |  |  The afterpotential is a period |
|  | A) | of increased depolarization. |
|  | B) | of hyperpolarization. |
|  | C) | when the cell is completely insensitive to additional stimuli. |
|  | D) | when a second action potential occurs. |
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24 |  |  The absolute refractory period ends when the activation gates of voltage-gated Na+ ion channels are __________ , and inactivation gates of voltage-gated Na+ ion channels are __________ . |
|  | A) | closed, closed |
|  | B) | closed, open |
|  | C) | open, closed |
|  | D) | open, open |
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25 |  |  The relative refractory period |
|  | A) | occurs before the absolute refractory period. |
|  | B) | continues until voltage-gated Na+ ion channels close. |
|  | C) | continues until voltage-gated K+ ion channels close. |
|  | D) | continues until voltage-gated Ca2+ ion channels close. |
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26 |  |  A stimulus just strong enough to produce a single action potential is a |
|  | A) | maximal stimulus. |
|  | B) | subthreshold stimulus. |
|  | C) | supramaximal stimulus. |
|  | D) | threshold stimulus. |
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27 |  |  During saltatory conduction, action potentials jump from |
|  | A) | one astrocyte to another. |
|  | B) | an axon to a dendrite. |
|  | C) | one internode to another. |
|  | D) | one node of Ranvier to another. |
|  | E) | one microglia cell to another. |
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28 |  |  Of these nerve fibers, which conduct action potentials the SLOWEST? |
|  | A) | myelinated nerve fibers |
|  | B) | large-diameter fibers |
|  | C) | type B fibers |
|  | D) | type C fibers |
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29 |  |  The axons that make up the white matter of the CNS form |
|  | A) | endoneurium. |
|  | B) | epineurium. |
|  | C) | ganglia. |
|  | D) | nerve fascicles. |
|  | E) | nerve tracts. |
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30 |  |  The outer layer of gray matter of the brain is called the |
|  | A) | cortex. |
|  | B) | ganglia. |
|  | C) | fascicle. |
|  | D) | nuclei. |
|  | E) | perineurium. |
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31 |  |  In nervous tissue, a nucleus is defined as a collection of |
|  | A) | myelinated axons in the CNS. |
|  | B) | gray matter in the PNS. |
|  | C) | gray matter in the CNS. |
|  | D) | white matter in the PNS. |
|  | E) | axons in the PNS. |
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32 |  |  At the synapse, synaptic vesicles are found in the |
|  | A) | postsynaptic cell. |
|  | B) | presynaptic cell. |
|  | C) | synaptic cleft. |
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33 |  |  After being released, neurotransmitters bind to receptors on the |
|  | A) | postsynaptic membrane. |
|  | B) | neuromodulators. |
|  | C) | synaptic cleft. |
|  | D) | synaptic vesicle. |
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34 |  |  Acetylcholinesterase, monoamine oxidase (MAO), and catechol-O-methyltransferase are |
|  | A) | neurotransmitters. |
|  | B) | enzymes that break down neurotransmitters. |
|  | C) | enzymes that act as neuromodulators. |
|  | D) | enzymes that could produce an EPSP. |
|  | E) | substances that could produce an IPSP. |
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35 |  |  Which of these is NOT a neurotransmitter? |
|  | A) | glutamate |
|  | B) | norepinephrine |
|  | C) | acetylcholine |
|  | D) | myelin |
|  | E) | dopamine |
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36 |  |  Which of these characteristics can be produced by an EPSP? |
|  | A) | local hyperpolarization |
|  | B) | decreased excitability of neuron |
|  | C) | increased permeability of postsynaptic membrane to K+ and Cl- ions |
|  | D) | local depolarization |
|  | E) | all of these |
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37 |  |  If a neurotransmitter binds to receptor molecules that open K+ ion channels, the result is |
|  | A) | an excitatory postsynaptic potential (EPSP). |
|  | B) | an inhibitory postsynaptic potential (IPSP). |
|  | C) | no change. |
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38 |  |  When two action potentials arrive in very close succession at a single presynaptic terminal, |
|  | A) | an IPSP is produced. |
|  | B) | the second action potential cancels the first. |
|  | C) | spatial summation occurs. |
|  | D) | temporal summation occurs. |
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39 |  |  If an action potential that results in an IPSP and an action potential that results in an EPSP both reach a postsynaptic membrane at the same time, the most likely result is |
|  | A) | an action potential in the postsynaptic cell. |
|  | B) | two action potentials in the postsynaptic cell. |
|  | C) | no action potential in the postsynaptic cell. |
|  | D) | a reverse action potential in both presynaptic cells. |
|  | E) | temporal summation. |
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40 |  |  Which of these combinations represents a convergent pathway in the nervous system? |
|  | A) | One presynaptic neuron synapses with 4 postsynaptic neurons. |
|  | B) | One presynaptic neuron synapses with one postsynaptic neuron. |
|  | C) | Three presynaptic neurons synapse with one postsynaptic neuron. |
|  | D) | An afferent neuron synapses with an association neuron. |
|  | E) | Collateral axons from a presynaptic neuron synapse with several postsynaptic neurons. |
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